Facts

Why Do Kids Get Cancer?

by St. Baldrick's Foundation
September 13, 2019

Why do kids get cancer? That’s the question we asked Dr. John Maris, who co-leads the St. Baldrick’s Foundation – Stand Up to Cancer Pediatric Cancer Dream Team*. Researchers like Dr. Maris are working hard to find the answer to this question because it could hold the key to cures for kids’ cancer.

Why Do Kids Get Cancer

Why do kids get cancer? In short, there’s no single, easy answer.

The answer is complicated, said Dr. Maris.

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News

Your Donations Make Research Possible – and That Research is Shared Worldwide

by Becky C. Weaver, Chief Mission Officer, St. Baldrick's Foundation
August 14, 2019

Most St. Baldrick’s Foundation supporters know they are making hundreds of childhood cancer research projects possible. They may not realize the research they supported has been published in more than 1,350 research publications since 2005.

We’ll touch on just a few of those here. But first, why are publications important and how do they help find cures for childhood cancer? The answer started long ago.

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Childhood Cancer

Two Canadian Pediatric Cancer Researchers Share 2019 US/Canada Arceci Award

by St. Baldrick's Foundation
May 8, 2019

“Same old, same old … doesn’t count.” Bob Arceci didn’t think that old methods were going to tackle pediatric cancers. As you can hear him talk about in this video, he was looking for new ideas, for thinking that wasn’t just “out of the box,” but never really in the box in the first place.

Drs. Shlien and Daugaard are shown accepting the Robert J. Arceci Innovation Award.Drs. Shlien and Daugaard accept the Robert J. Arceci Innovation Award.

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Childhood Cancer

When Research Offers Hope, Parents Continue to Advance the Mission

by Carlos Sandi, Dream Team Patient Advocate
October 23, 2018

*Formerly known as the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, this team is now the St. Baldrick’s EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer).

I was recently invited to serve as a patient family advocate for the St. Baldrick’s / Stand Up to Cancer Pediatric Cancer Dream Team representing the National Cancer Institute. If you’re not familiar with the Dream Team and what they’re doing, it’s worth taking a few minutes to read up on the project.

In short, it’s a multi-institutional effort to accelerate cures for childhood cancer by sharing the skill, knowledge and unique resources of 8 top-notch research institutions.

Carlos Sandi with his son, Phineas

Carlos Sandi with his son, Honored Kid and Ambassador Phineas.

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Childhood Cancer

New Immunotherapy Breakthrough Could Bring Hope to Kids With DIPG

by Erinn Jessop, St. Baldrick's Foundation
September 21, 2018

Maddy

Honored Kid Madelyn was diagnosed with DIPG in 2010. A fashionista with a big spirit and an equally big heart, Maddy was an inspiration to those around her. She passed away in November 2011 after an 18-month battle with DIPG.

No child has ever survived a diffuse intrinsic pontine glioma brain tumor, commonly called DIPG.

This aggressive pediatric brain cancer multiplies in the brainstem, which controls some of our most basic functions for living – our breathing, heart rate, blood pressure and ability to swallow and speak.  And because the cancer is so intertwined with its delicate surroundings, DIPG is often inoperable.

A DIPG diagnosis and a zero percent survival rate has remained the reality for kids and families for decades.

But what if there might be hope? What if that hope came from within the child’s own body?

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Childhood Cancer

The Dream Team is Back — Thanks to You!

by Becky C. Weaver, Chief Mission Officer, St. Baldrick's Foundation
April 15, 2018

Formerly known as the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, this team is now the St. Baldrick’s EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer).

I have something exciting to tell you, but first, here’s something I heard and quickly scribbled down during a meeting about research priorities: “It’s like we caught lightning in a bottle – and you just don’t know when that will happen again.”

That was one of our expert advisers talking about the amazing, incredibly fast and impactful work of the Stand Up to Cancer – St. Baldrick’s Pediatric Cancer Dream Team, funded jointly by the two organizations from 2013 through 2017.  It was such a perfect description, it has stuck with me for more than a year.

This team of 150 researchers from eight institutions across North America has been working on new immunotherapy treatments for childhood cancers.  In less than four years, their work is already saving lives.

Austin wears a face mask

Honored Kid Austin was diagnosed with a high-risk form of acute lymphoblastic leukemia when he was 2 years old. Now a survivor, he was one of the first kids treated on a trial of the immunotherapy Kymriah, which was developed with help from the Dream Team.

Every one of the experts who had looked closely at the team’s work agreed that this was work that must continue.  To me, it was only natural for St. Baldrick’s to make that happen.  And by St. Baldrick’s, I mean you – our donors and volunteers who make the funding possible.

So, I’m thrilled to announce that the Dream Team is back – with a new name and a continuing determination to find cures for childhood cancers.

The St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team will continue from 2018 through 2022, with primary support from St. Baldrick’s.

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Childhood Cancer

Kymriah’s Journey From Lab to Lifesaver: FDA Approval and Beyond [Part Four]

by Erinn Jessop, St. Baldrick's Foundation
January 19, 2018

From its inaugural Phase 1 clinical trial through its successful Phase 2 trial, we have traced the path of Kymriah, a recent immunotherapy and gene therapy breakthrough for kids with high-risk leukemia and few options, like Honored Kids Austin and Ori. (Read the whole series here.) Now, with a historic decision made in August, we are at the end of our story, but not at the end of the story of Kymriah. Instead, Kymriah’s is just beginning – and starting a new chapter of hope for kids with cancer.

A collage of Austin and Ori

Austin (left) and Ori (right) are both alive today thanks to Kymriah and their participation in the Phase 1 and Phase 2 trials.

On August 30, 2017, big news rippled through the childhood cancer community. On that late summer day – before the start of Childhood Cancer Awareness Month – the FDA made a historic move that changed the landscape of childhood cancer research forever.

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Childhood Cancer

Kymriah’s Journey From Lab to Lifesaver: The Phase 2 Trial [Part Three]

by Erinn Jessop, St. Baldrick's Foundation
January 11, 2018

Over a series of four blogs — catch up with parts one and two about the Phase 1 trial — we are tracing the path of Kymriah, a recent immunotherapy and gene therapy breakthrough for kids with high-risk leukemia, like Honored Kid Ori.


After relapsing for the second time and with his cancer spreading to his nervous system, Ori’s best chance at life was a Phase 2 trial of this experimental CAR T cell therapy. With a sunny attitude and staggering strength of spirit, Ori gave this new treatment a shot – with astonishing results.

Ori smiles in bed

Ori was in cancer treatment for much of his young life and throughout the journey, his strength and positive attitude have been remarkable. “He has been through so much, but has done it all with a great attitude and a smile on his face,” said his mom, Kaye.

When a child with cancer relapses the first time, their treatment options shrink. But when a child with cancer relapses again, their options and chances at survival don’t just shrink – they’re nearly extinguished. That is what happened to Ori.

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Childhood Cancer

St. Baldrick’s Top 10 Highlights of 2017

by Erinn Jessop, St. Baldrick's Foundation
January 8, 2018

2017 was a big year, full of breakthroughs, incredible stories and some pretty amazing achievements in the childhood cancer world. Join us as we reflect on St. Baldrick’s top 10 highlights of the past year — and make sure you give yourself a pat on the back, because much of this was possible because of YOU!

St. Baldrick's 2017 Highlights

Are you ready to take a trip down memory lane? Here we go …

1) Passage of the RACE Act

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Why I Give

Your Donation to a Shavee Matters, and Here’s Why

by St. Baldrick's Foundation
January 3, 2018

Someone you know is shaving their head for childhood cancer research and is asking YOU for a donation. But why should you give?

Why donate to St. Baldrick's for childhood cancer research?

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