Facts

What is Sarcoma?

by Jeffrey Toretsky, M.D.
June 30, 2020
what is sarcoma

Dr. Jeffrey Toretsky is a St. Baldrick’s researcher at the Georgetown Lombardi Comprehensive Cancer Center in Washington, D.C. He explains what sarcoma is, how it’s diagnosed and treated, and how research is helping kids and adults with this type of cancer.

What is sarcoma?

A sarcoma is a bumpy tumor that occurs in the connective tissues (nerves, muscles and bones) anywhere in the body.

Sarcomas are rare, especially in young children. In kids between 10 and 20, sarcomas make up about 20-25% of childhood cancer diagnoses.

Sarcomas can start off being tiny lumps that you can’t feel. They can spread through the body, or metastasize, before they grow big enough to be seen.

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Facts

What Is Retinoblastoma?

by Murali Chintagumpala, M.D. and Carlos Rodriguez-Galindo, M.D.
May 11, 2020

Dr. Chintagumpala’s specific interests include the management of children with all brain tumors, retinoblastoma, bone tumors and kidney tumors. He serves as chair of the Retinoblastoma Sub-Committee for the Children’s Oncology Group and is a leader in conducting clinical trials involving children with brain tumors and Retinoblastoma.

Dr. Rodríguez-Galindo is a member of the St. Baldrick’s Scientific Advisory Committee. His research focuses on retinoblastoma, bone sarcomas, histiocytic disorders and rare childhood cancers.

what is retinoblastoma

What is Retinoblastoma?

Retinoblastoma is a cancer of the eye that only occurs in children and typically in very young children. Two-thirds of retinoblastoma patients are diagnosed before they’re 2 years old and more than 90% are diagnosed before turning 5.

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Facts

What Is Medulloblastoma?

by Elias Sayour, M.D., Ph.D. and Agnes Petrosiute, M.D.
May 1, 2020

Dr. Sayour and Dr. Petrosiute are both St. Baldrick’s Scholars. This blog was written by Dr. Petrosiute in May 2014 and updated in April 2020 by Dr. Sayour.

What is medulloblastoma?

Medulloblastoma is the most common malignant brain tumor in children. It originates in the back part of the brain called the cerebellum. In up to 1/3 of cases, it can spread to other parts of the brain and spinal cord. Most cases are diagnosed before age 10.

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Facts

What Is Wilms Tumor?

by Elizabeth Perlman, MD and Jeffrey S. Dome, MD, PhD.
March 10, 2020
What-Is-Wilms-Tumor.png

What is Wilms tumor?

Wilms tumor is a cancer of the kidney. It is one of the most common types of childhood cancer, with approximately 500 new patients a year in the United States alone. It was named after German surgeon Max Wilms, who is credited with discovering the cancer in 1899. There are several other less common types of kidney cancer that affect children and teenagers. These include clear cell sarcoma, malignant rhabdoid tumor, and renal cell carcinoma.

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Facts

What You Should Know About Research into Rare Pediatric Cancers

by Becky C. Weaver, Chief Mission Officer, St. Baldrick's Foundation
February 25, 2020

Rare Disease Day is observed on the last day of February, but the St. Baldrick’s Foundation fights rare diseases year-round.

What is rare disease?

When it comes to cancer, or even diseases as a whole, “rare” is a misleading word.

In the U.S., a rare disease is defined as “any disease or condition that affects fewer than 200,000 people in the United States, or about 1 in 1,500 people.” About 72% of rare diseases are genetic, and of those, 70% start in childhood.

Worldwide, people with rare diseases make up less than 6% of the population. But more than 6,000 rare diseases have been identified so far, and they affect more than 300 million around the world. If these people were a country, they would be the world’s third largest nation.

rare disease stats

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Facts

What Is Neuroblastoma?

by St. Baldrick's Foundation
January 31, 2020
What is Neuroblastoma graphic

Susan L. Cohn, M.D., chair of the St. Baldrick’s Scientific Advisory Committee and world renowned neuroblastoma expert, explains what neuroblastoma is and how St. Baldrick’s research is contributing to better outcomes for patients.

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Facts

What is Hepatoblastoma?

by Edward Prochownik, M.D., Ph.D.
October 8, 2019
What is Hepatoblastoma?Dr. Edward Prochownik is a past St. Baldrick’s Research Grant recipient and is The Paul C. Gaffney Professor of Pediatrics and Professor of Microbiology & Molecular Genetics at Children’s Hospital of Pittsburgh. In this blog post, he answers the question “What Is Hepatoblastoma,” and shares some other information about the cancer, its treatment, prevalence, and why research is so important.

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Childhood Cancer

Pediatric Cancer Dream Team Works Toward More Breakthroughs

by St. Baldrick's Foundation
October 2, 2019

When the St. Baldrick’s Foundation — Stand Up 2 Cancer Pediatric Cancer Dream Team was created in 2013, the idea was to pursue breakthroughs, specifically in the area of immunotherapy enabled by the application of modern genomic technologies. Now, with St. Baldrick’s as the primary funder and each member institution also investing financially — the Dream Team looks to build on the tremendous momentum in immunotherapy for childhood cancers.

Dream Team Map

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Facts

Project:EveryChild

by Becky C. Weaver, Chief Mission Officer, St. Baldrick's Foundation
September 18, 2019

Project:EveryChild is an ambitious initiative to find better cures for every type of childhood cancer, no matter how rare. And it is only possible because of the combined efforts of researchers, families of children with cancer, and you.

There are about 14,000 new cases of childhood cancer each year in the United States, and the most common – acute lymphoblastic leukemia – accounts for about 3,500 of those. But there are some types of cancer that are diagnosed in fewer than 100 children a year. The rarer the disease, the more challenging it is for researchers to make progress.

No matter how common or rare, each child deserves the best chance at a cure. That’s where Project:EveryChild comes in.

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Facts

Why Do Kids Get Cancer?

by St. Baldrick's Foundation
September 13, 2019

Why do kids get cancer? That’s the question we asked Dr. John Maris, who co-leads the St. Baldrick’s Foundation – Stand Up to Cancer Pediatric Cancer Dream Team. Researchers like Dr. Maris are working hard to find the answer to this question because it could hold the key to cures for kids’ cancer.

Why Do Kids Get Cancer

Why do kids get cancer? In short, there’s no single, easy answer.

The answer is complicated, said Dr. Maris.

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