Research Outcomes: Progress from Bench to Bedside
With your help researchers continue to answer questions, seek out cures, and reduce long-term effects of treatment. Four exciting research outcomes you made possible are detailed below:
The Dream Team’s Impact – in a Father’s Own Words
Formerly known as the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, this team is now the St. Baldrick’s EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer).
What does your support of childhood cancer research really mean? See what Carlos Sandi has to say about what a difference the St. Baldrick’s Foundation and specifically the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, have made to his family.
Living Proof That Thanks to The DREAM TEAM… Dreams Do Come True
Formerly known as the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, this team is now the St. Baldrick’s EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer).
What do you do when you’ve been told your child has maybe 3 to 6 months to live? As the saying goes, “You get busy living or you get busy dying.” That’s the situation Kim and Jeff Schuetz were put in when their son Austin relapsed not once, but twice after treatment for Acute Lymphoblastic Leukemia (ALL), the most common type of childhood cancer.
Dream Team News: Progress in a Deadly Pediatric Brain Tumor
Formerly known as the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, this team is now the St. Baldrick’s EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer).
The Science of Self Defense
One goal of science and research is to make the impossible, possible. So, what if we could train the body to fight off cancer itself? To ferociously attack what is attacking it. It would be a game changer and that’s exactly the kind of revolutionary research St. Baldrick’s supporters are making possible through the St. Baldrick’s – Stand Up to Cancer Pediatric Dream Team.
One of the Dream Team’s research studies was so important, it was recently featured on the cover of the prestigious scientific journal, Nature Medicine. The article outlines new advances to train immune cells in pediatric patients to target deadly brain tumors known as atypical teratoid/rhabdoid tumors (ATRT tumors). These tumors develop in babies and toddlers, who currently only survive an average of 17 months.
Discoveries that Shift Paradigms with Dr. Poul Sorensen
Formerly known as the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, this team is now the St. Baldrick’s EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer).
St. Baldrick’s is all about shifting paradigms. When three men decided to shave heads at their industry’s March 17, 2000 St. Patrick’s Day party, they didn’t set out to change the landscape of childhood cancer research funding. But today the St. Baldrick’s Foundation is the largest non-government funder of childhood cancer research grants.
Twenty years later, the paradigm shifts keep coming, and Poul Sorensen, MD, PhD has been a part of several of them. Last month we joined some very special guests on a visit to his lab at the University of British Columbia, where he is a Professor of Pathology and holds the Johal Endowed Chair in Childhood Cancer Research.
Dr. Poul Sorensen (right) with his Co-Principal Investigator, Dr. Mads Daugaard (left).
Interview with a Researcher: Meet Dr. Shannon Maude from CHOP
Editor’s Note: Shannon Maude, M.D., Ph.D. is a physician scientist at Children’s Hospital of Philadelphia (CHOP), where she has specialized in treating children with acute lymphocytic leukemia, or ALL. A member of the St. Baldrick’s Foundation — Stand Up To Cancer Pediatric Cancer Dream Team*, she got her start in pediatric cancer research in part thanks to a St. Baldrick’s Scholar grant.
Two years of her scholar grant were funded by the Rally for Ryan Hero Fund. Ryan’s mom reports that he is “doing great” after his latest checkup in August 2019.
We recently discussed her career and her work with children impacted by ALL. An edited transcript of that discussion is below.
Dr. Shannon Maude credits a St. Baldrick’s Scholar grant to her start in pediatric cancer research.
Research Outcomes: Next in a Series
In August of 2019, we blogged about several research outcomes that were fueled by St. Baldrick’s donations and published in scientific journals so that other researchers can build upon them. Research publications are a major way that science moves forward.
With more than 200 new publications a year resulting from research supported by St. Baldrick’s, we’ve decided to make this an occasional series, to highlight some of the most interesting outcomes you’ve made possible.
Why the Pediatric Cancer Dream Team Incorporates Patient Advocates into the Research Process
Formerly known as the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, this team is now the St. Baldrick’s EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer).
“I’m an accidental tourist in the childhood cancer world,” says Patrick Sullivan, who chairs the Patient Advocacy committee for the St. Baldrick’s Foundation — Stand Up 2 Cancer Pediatric Cancer Dream Team. “It’s not a place I’d ever thought I’d be in, until I heard that my son had rhabdomyosarcoma in 2007.”
Patrick Sullivan and his son, Finn.
Patrick’s role is more than just tourist, though. When the Pediatric Cancer Dream Team was created, its goal was to push the envelope, to marry the emerging fields of genomics and immunotherapy to create targeted therapies for cancers. It was also important to the Dream Team to involve patient advocates, to inspire and work alongside the researchers, to maximize the Dream Team’s success. Along the way, each researcher was paired with a young investigator on the team, to help the advocates better understand the science and to help the young investigators better communicate their work to families and the lay public.
Pediatric Cancer Dream Team Works Toward More Breakthroughs
Formerly known as the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, this team is now the St. Baldrick’s EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer).
When the St. Baldrick’s Foundation — Stand Up 2 Cancer Pediatric Cancer Dream Team was created in 2013, the idea was to pursue breakthroughs, specifically in the area of immunotherapy enabled by the application of modern genomic technologies. Now, with St. Baldrick’s as the primary funder and each member institution also investing financially — the Dream Team looks to build on the tremendous momentum in immunotherapy for childhood cancers.
Why Do Kids Get Cancer?
Why do kids get cancer? That’s the question we asked Dr. John Maris, who co-leads the St. Baldrick’s Foundation – Stand Up to Cancer Pediatric Cancer Dream Team*. Researchers like Dr. Maris are working hard to find the answer to this question because it could hold the key to cures for kids’ cancer.
Why do kids get cancer? In short, there’s no single, easy answer.
The answer is complicated, said Dr. Maris.
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