News

Champions Needed: The Future of Childhood Cancer Research is at Stake

by Kathleen Ruddy, CEO, St. Baldrick's Foundation
March 17, 2017

This week the St. Baldrick’s Foundation calls to your attention two urgent challenges.

First, the new federal budget proposal calls for a cut of nearly 20% for the National Institutes of Health (NIH), the largest funding source for childhood cancer research.

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Advocacy

A ‘Meeting of the Minds’ to Look to the Future for Kids With Cancer

by Becky C. Weaver, Chief Mission Officer, St. Baldrick's Foundation
November 7, 2016

What happens when a group of experts come together to discuss developments in childhood cancer research and advocacy? Some inspiring conversations about new data, drugs and therapies, important childhood cancer legislation, and more — all to make sure we’re making the best investments with YOUR donations. Get the scoop on our 2016 Research and Advocacy Priorities Summit below.

St. Baldrick's 2016 Research and Advocacy Priorities Summit

Every couple of years, St. Baldrick’s brings together our experts to take stock of what we’re doing now, and to look to the future of childhood cancer research. We examine what we are doing well, what we can do better, and what we need to do to help kids with cancer not only survive, but thrive.

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Facts

The Fight’s Never Over: The Two Biggest Threats Facing Childhood Cancer Survivors

by Erinn Jessop, St. Baldrick's Foundation
March 31, 2016

Surviving childhood cancer isn’t the end of the fight. As survivors age, heart disease and secondary cancers become two big risks, often caused by the very treatment needed to save their lives. Read on to learn more about the two main threats to survivors and how St. Baldrick’s researchers are working to help.

Ambassador Grace holds a sign that reads: Thrive

Since surviving a brain tumor as a child, Ambassador Grace has dealt with long-term effects from her treatment.

After beating childhood cancer, survivors should be living long and healthy lives, but that isn’t always the case.

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Research

What Is Genomics?

by Rebecca Bernot, St. Baldrick's Foundation
January 3, 2014

What is genomics?

Dr._Parsons

Dr. Parsons, a genomics expert on the Stand Up To Cancer – St. Baldrick’s Pediatric Cancer Dream Team.

When it comes to childhood cancer, there’s a lot we’ve learned over the years — and a lot we still don’t know.

For example, we know that childhood cancer is caused by genetic mutations. What we don’t know is how or why most of those mutations occur.

And we’re still trying to figure out what the mutations mean — in terms of the cancer and its ability to thrive, and in terms of our bodies and their ability to overcome disease.

That’s the focus of genomics, explains Dr. Donald Parsons, the principal investigator at Baylor College of Medicine for the Stand Up To Cancer – St. Baldrick’s Pediatric Cancer Dream Team.

“Genomics is the study on a large scale of all the genetic changes that occur in a patient’s DNA,” Dr. Parsons says. “It really tries to look at — in a single patient or across a group of patients — all the different changes that occur and how they might interact with each other.”

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Research

St. Baldrick’s Researcher Uses Novel Drug Screening Method for Potential New ALL Treatments

by Rebecca Bernot, St. Baldrick's Foundation
December 13, 2013

Your donation to St. Baldrick’s funds pediatric cancer research. Donate now.

ALL_research
Historically, scientists have largely relied on nature as a source for treatments for various ailments. The modern-day antibiotic penicillin, for example, is derived from mold. Opium made from poppy seeds was cultivated and used for its pain relieving properties by ancient civilizations, and it is still used today to make morphine, codeine, and other painkillers in the opioid class.

Now, thanks to advances in modern chemistry, scientists are able to synthesize hundreds of thousands of known drug compounds and store them in vast chemical libraries. With the aid of highly technical robots and computers, researchers can test the entire library for effectiveness in treating a certain disease in a process known as high-throughput screening.

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Research

St. Baldrick’s Researcher Developing New Targeted Therapies for Ewing Sarcoma

by Rebecca Bernot, St. Baldrick's Foundation
December 2, 2013

Your donation to St. Baldrick’s supports pediatric cancer research. Donate now.

Ewing_sarcoma_research
There are things we can do that will increase our risk for cancer later in life, like tanning and smoking cigarettes. But childhood cancer is a different story.

Pediatric cancers are caused by genetic mutations. “However, since these mutations are unique to pediatric cancer, unique drugs need to be developed to treat these cancers,” explains Patrick Grohar, M.D., Ph.D., assistant professor of pediatric hematology-oncology at Vanderbilt University and a St. Baldrick’s research grant recipient.

Dr. Grohar is working to develop new drugs that target one particular mutation found in Ewing sarcoma tumors, ultimately yielding more effective and less toxic treatments for this form of childhood cancer.

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News

Every Cent Matters in the Fight Against Childhood Cancers

by Becky C. Weaver, Chief Mission Officer, St. Baldrick's Foundation
November 16, 2012

Dear St. Baldrick’s Community,

I am forever grateful that you have chosen to join us in the fight against childhood cancers. You give your time and lend your voice, but most importantly, you place your trust in us to use wisely every cent you raise.

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