News

And the International Arceci Award Goes to…

by Erinn Jessop, St. Baldrick's Foundation
October 13, 2017

Usually, we pick one international winner of the Robert J. Arceci Innovation Award, but what happens when there are two equally deserving researchers with big ideas and big hearts for kids with cancer? Read on to find out!

Dr. Franck Bourdeaut and Dr. Jan-Henning Klusmann

After being nominated for the International Robert J. Arceci Innovation Award, (left) Dr. Franck Bourdeaut and (right) Dr. Jan-Henning Klusmann were both selected by a committee of experts and are being presented with the award today at the annual conference for the International Society of Paediatric Oncology.

Dr. Robert Arceci was a passionate innovator who dreamed big. He was a pioneer who knew that kids with cancer deserve better than what doctors can offer them and that breakthroughs are born from taking risks.

That’s why the international winner of the award established in his memory – the Robert J. Arceci Innovation Award – is given the resources and the freedom to follow their curiosity, pioneering spirit, and their passion for kids’ cancer research, wherever it leads.

Except this year, it’s winners of the Robert J. Arceci Innovation Award!

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Facts

A Letter to You, From David’s Mom and Dad

by St. Baldrick's Foundation
September 12, 2017

Ever wonder if your contributions make a real difference? That money you donated to the St. Baldrick’s Foundation – did it really accomplish anything?

David with his mom Susan at an event

David squeezes his mom, Susan, tight during a fundraising event.

Let us tell you about our son, David.

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Research

Meet the St. Baldrick’s Innovation Award Winners

by Erinn Jessop, St. Baldrick's Foundation
August 11, 2017

What do researchers Dr. Alex Huang and Dr. Carl Allen have in common? Passion, curiosity, drive, brilliant ideas, a desire to help kids — the list goes on! And now there’s something else. They are both recipients of the first St. Baldrick’s Innovation Award. What do they want to do with this unique grant? Read on to find out.

Dr. Carl Allen and Dr. Alex Huang

Dr. Carl Allen (left) is an associate professor at Texas Children’s Cancer Center and one of the investigators involved in the North American Consortium for Histiocytosis (NACHO), which received a St. Baldrick’s Consortium Grant. St. Baldrick’s researcher Dr. Alex Huang (right) is a professor of pediatrics at Case Western Reserve University School of Medicine and a 10-time shavee with St. Baldrick’s.

St. Baldrick’s researchers Dr. Alex Huang and Dr. Carl Allen work on different projects, in different labs about 1,300 miles away from each other.

Dr. Huang primarily studies how immunotherapy can help kids with cancer, while Dr. Allen studies Langerhans Cell Histiocytosis or LCH, which is caused by out-of-control immature white blood cells. The disorder can cause inflammatory tumors, damage organs and even cause brain degeneration in some patients.

The two researchers may work in different areas on different projects, but since the start of their careers in medicine, they’ve shared a goal — to help sick kids get better. And now they have something else in common.

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News

Announcing St. Baldrick’s 2017 Summer Grants [VIDEO]

by St. Baldrick's Foundation
July 25, 2017

When the school bell rang for summer break, what did you do? Swim like a fish? Swing as high as the stars? Swoon over your summer love? Press pause on reliving those childhood glory days for a second, because we’ve got great news. Together, we are helping kids with cancer get back to being kids — all that summer fun included. Say hello to our 2017 Summer Grants!

2017 Summer Grants

Dr. Hilary Marusak received a St. Baldrick’s Supportive Care Research grant for her work studying whether a martial arts therapy that focuses on meditation and breathing techniques can reduce pain — and pain’s negative long-term impact — in kids with cancer and survivors.

Today, St. Baldrick’s is proud to announce our latest round of grants — our 2017 Summer Grants, totaling $23.5 million.

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News

Champions Needed: The Future of Childhood Cancer Research is at Stake

by St. Baldrick's Foundation
March 17, 2017

This week the St. Baldrick’s Foundation calls to your attention two urgent challenges.

First, the new federal budget proposal calls for a cut of nearly 20% for the National Institutes of Health (NIH), the largest funding source for childhood cancer research.

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Advocacy

A ‘Meeting of the Minds’ to Look to the Future for Kids With Cancer

by St. Baldrick's Foundation
November 7, 2016

What happens when a group of experts come together to discuss developments in childhood cancer research and advocacy? Some inspiring conversations about new data, drugs and therapies, important childhood cancer legislation, and more — all to make sure we’re making the best investments with YOUR donations. Get the scoop on our 2016 Research and Advocacy Priorities Summit below.

St. Baldrick's 2016 Research and Advocacy Priorities Summit

Every couple of years, St. Baldrick’s brings together our experts to take stock of what we’re doing now, and to look to the future of childhood cancer research. We examine what we are doing well, what we can do better, and what we need to do to help kids with cancer not only survive, but thrive.

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Facts

The Fight’s Never Over: The Two Biggest Threats Facing Childhood Cancer Survivors

by Erinn Jessop, St. Baldrick's Foundation
March 31, 2016

Surviving childhood cancer isn’t the end of the fight. As survivors age, heart disease and secondary cancers become two big risks, often caused by the very treatment needed to save their lives. Read on to learn more about the two main threats to survivors and how St. Baldrick’s researchers are working to help.

Ambassador Grace holds a sign that reads: Thrive

Since surviving a brain tumor as a child, Ambassador Grace has dealt with long-term effects from her treatment.

After beating childhood cancer, survivors should be living long and healthy lives, but that isn’t always the case.

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Research

What Is Genomics?

by St. Baldrick's Foundation
January 3, 2014

What is genomics?

Dr._Parsons

Dr. Parsons, a genomics expert on the Stand Up To Cancer – St. Baldrick’s Pediatric Cancer Dream Team.

When it comes to childhood cancer, there’s a lot we’ve learned over the years — and a lot we still don’t know.

For example, we know that childhood cancer is caused by genetic mutations. What we don’t know is how or why most of those mutations occur.

And we’re still trying to figure out what the mutations mean — in terms of the cancer and its ability to thrive, and in terms of our bodies and their ability to overcome disease.

That’s the focus of genomics, explains Dr. Donald Parsons, the principal investigator at Baylor College of Medicine for the Stand Up To Cancer – St. Baldrick’s Pediatric Cancer Dream Team.

“Genomics is the study on a large scale of all the genetic changes that occur in a patient’s DNA,” Dr. Parsons says. “It really tries to look at — in a single patient or across a group of patients — all the different changes that occur and how they might interact with each other.”

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Research

St. Baldrick’s Researcher Uses Novel Drug Screening Method for Potential New ALL Treatments

by St. Baldrick's Foundation
December 13, 2013

Your donation to St. Baldrick’s funds pediatric cancer research. Donate now.

ALL_research
Historically, scientists have largely relied on nature as a source for treatments for various ailments. The modern-day antibiotic penicillin, for example, is derived from mold. Opium made from poppy seeds was cultivated and used for its pain relieving properties by ancient civilizations, and it is still used today to make morphine, codeine, and other painkillers in the opioid class.

Now, thanks to advances in modern chemistry, scientists are able to synthesize hundreds of thousands of known drug compounds and store them in vast chemical libraries. With the aid of highly technical robots and computers, researchers can test the entire library for effectiveness in treating a certain disease in a process known as high-throughput screening.

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Research

St. Baldrick’s Researcher Developing New Targeted Therapies for Ewing Sarcoma

by St. Baldrick's Foundation
December 2, 2013

Your donation to St. Baldrick’s supports pediatric cancer research. Donate now.

Ewing_sarcoma_research
There are things we can do that will increase our risk for cancer later in life, like tanning and smoking cigarettes. But childhood cancer is a different story.

Pediatric cancers are caused by genetic mutations. “However, since these mutations are unique to pediatric cancer, unique drugs need to be developed to treat these cancers,” explains Patrick Grohar, M.D., Ph.D., assistant professor of pediatric hematology-oncology at Vanderbilt University and a St. Baldrick’s research grant recipient.

Dr. Grohar is working to develop new drugs that target one particular mutation found in Ewing sarcoma tumors, ultimately yielding more effective and less toxic treatments for this form of childhood cancer.

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