Research

Neuroblastoma Expert to Lead Pediatric Dream Team

by St. Baldrick's Foundation
April 7, 2013

Formerly known as the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, this team is now the St. Baldrick’s EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer).

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Dr. John M. Maris, SU2C – St. Baldrick’s Pediatric Dream Team Leader

Dr. Crystal Mackall and Dr. John Maris will co-chair the SU2C-St. Baldrick’s Foundation Immunogenomics Dream Team.

Even before he started medical school, physician and scientist John M. Maris, MD, was interested in neuroblastoma, a cancer that starts in young nerve cells and can spread quickly through a child’s body. It is one of the most common cancers in children, and the most common cancer in infants.

As he continued studying the disease, Dr. Maris became convinced that neuroblastoma was a genetic disease and that genetic research could unlock new treatments for kids with cancer. Since then, Dr. Maris has devoted his career to curing neuroblastoma, a passion that has fueled over two decades of research.

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Research

Immunogenomics to Create New Therapies for High-Risk Childhood Cancers

by St. Baldrick's Foundation
April 7, 2013

Formerly known as the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, this team is now the St. Baldrick’s EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer).

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The Dream Team, funded by Stand Up 2 Cancer and the St. Baldrick’s Foundation, aims to establish genomics-based immunotherapy as the second revolution in childhood cancer. The following is adapted from the Dream Team’s own summary of its proposal.

Curative chemotherapy for cancer was first realized in children. Survival rates for many of the common cancers in children improved dramatically through the last part of the 20th century. However, those cure rates have plateaued since the 1990s, and for some childhood cancers, we have seen little to no improvements.

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Research

Announcing the Stand Up To Cancer – St. Baldrick’s Pediatric Cancer Dream Team [VIDEO]

by Kathleen Ruddy, CEO, St. Baldrick's Foundation
April 7, 2013

Formerly known as the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, this team is now the St. Baldrick’s EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer).

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I wish you could have been with us in the room when the first pediatric cancer Dream Team was announced, to be funded by the partnership of the St. Baldrick’s Foundation and Stand Up To Cancer (SU2C).

From a long list of innovative “big ideas,” the scientific reviewers representing both funding organizations had chosen the top four to submit detailed proposals. The experts agreed that any of these would be great investments, but for a grant of $14.5 million over four years, only one could be chosen.

The suspense ended with an enthusiastic round of applause when the winning Dream Team was announced at a reception tonight at the annual meeting of the American Association of Cancer Research (AACR). The evening’s emcee was actor Kyle MacLachlan, and speakers included Nobel Laureate Dr. Philip Sharp, St. Baldrick’s CEO Kathleen Ruddy, and 10-year-old cancer survivor Emma W. and her parents.

And the award goes to:

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Research

Behind the Scenes: Selecting a Dream Team

by Becky C. Weaver, Chief Mission Officer, St. Baldrick's Foundation
March 15, 2013

Formerly known as the St. Baldrick’s – Stand Up to Cancer Pediatric Cancer Dream Team, this team is now the St. Baldrick’s EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer).

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This is a cause that makes people do things they never thought they’d do.  I was reminded of that in a different way on February 27.

The researcher clearly was surprised with himself. He smiled, looked at Dr. Phillip Sharp, and said politely, “Well, I’ve never argued with a Nobel Laureate before, but…” — and then made a point for the group to consider. It was a day full of scientific debate — lively, respectful, and thorough.

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Kids with Cancer

Justin’s year in the fight against neuroblastoma

by St. Baldrick's Foundation
December 21, 2012

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By Lori Miller, mother to Justin, the childhood cancer fighting ninja and 2012 Ambassador Kid

As I sit here and reflect on our last year, I can’t help but be overwhelmed with an extreme range of emotions. I can truthfully admit I wasn’t sure if Justin would be here this Christmas, not that I didn’t have hope and not that I didn’t think he could prevail, but because we didn’t have any treatment options available to us. Justin had multiple relapses, weakened bone marrow, low platelets and an ANC that was consistently low. We mustered through each day over the last holiday season, put a smile on our faces and prayed for something to turn up. Justin wasn’t ready to give up; I wasn’t ready to give up.

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Childhood Cancer

Childhood Cancer Research Funding and the State of the Fight Against Kids’ Cancer [INFOGRAPHIC]

by St. Baldrick's Foundation
October 2, 2012
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by Dr. Robert Arceci, M.D., Ph.D., King Fahd Professor of Pediatric Oncology, co-director of the Michael J. Garil Leukemia Survivor’s Program at Johns Hopkins University School of Medicine and chair of the St. Baldrick’s Foundation Scientific Advisory Committee.

In my perfect world, I imagine a day when a child comes to my office with a cancer diagnosis and I can prescribe a 10-day course of medicine, just like amoxacillin for strep throat, and he or she is cured.

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Kids with Cancer

Justin Miller on the Stand Up To Cancer Red Carpet [VIDEO]

by St. Baldrick's Foundation
September 12, 2012

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By Lori Miller, mother to Justin, St. Baldrick’s Foundation 2012 Ambassador Kid and Childhood Cancer Fighting Ninja

First and foremost, I want to thank the St. Baldrick’s Foundation and Stand Up To Cancer for allowing us to represent the collaboration of these two organizations on the Stand Up To Cancer Broadcast last Friday evening. We were proud to represent our beautiful ANGEL friends, our fellow cancer fighters, and those who will be following us in the future. We need cures now and the time is now, especially during Childhood Cancer Awareness Month, to stand up and tell the world about childhood cancer.

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