Grants Search Results

Access to early phase trials is vital to the treatment of pediatric cancers that have relapsed or do not respond to standard therapies. The pediatric oncology department at Children's Hospital and Research Center Oakland has made strides to develop an early phase therapeutics program for brain tumors, other solid tumors and relapsed leukemia in conjunction with collaborators on the West Coast. This grant supports the infrastructure to start and maintain the program.

This grant funds a pediatric specific pharmacist at this institution to improve patient outcomes and care.

This grant supports a Clinical Research Associate dedicated to Phase I, II, and III brain tumor clinical trials, to ensure that more kids can be treated on clinical trials.

This grant supportss a Clinical Research Coordinator to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

Funding from the St. Baldrick's Foundation has taken two very small programs at UIC and Rush Medical Centers, merged them and brought Stroger Medical Center into the fold to forge a single entity for purposes of participation in Children's Oncology Group clinical trials. This support of necessary personnel has significantly increased clinical trial participation for patients who otherwise might not have access to them.

This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant funds a Clinical Research Nurse to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant funds a clinical research coordinator to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant funds a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant funds personnel to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant helps provide necessary resources for the Childhood Cancer Survivorship Program at this institution. The program provides survivors the support, treatment and education they need to prevent and address these late effects.

This grant supports an adolescent-young Adult (AYA) liaison to ensure that more AYAs can be treated on clinical trials, often their best hope for a cure.

This grant helps provide necessary resources to help establish Nevada's first Pediatric Brain Tumor Program.

Genetic studies have identified the molecular causes of childhood cancers such as T-cell leukemia and neuroblastoma. A recurrent theme in these cancers is abnormal activation of the MYC gene. Accordingly, researchers like Dr. Wendel have spent much time and effort in trying to identify inhibitors of MYC as they believe these could be very powerful therapies for these childhood cancers. Dr. Wendel and his colleagues recently found a new way to block the production of MYC using a natural compound. The natural product is rare and hard to come by and therefore Dr. Wendel and his colleagues are exploring ways to generate synthetic drugs based on this plant product. With support from the St. Baldrick’s Foundation they are working to bring this new strategy to the clinic. They focus especially on heavily pre-treated and relapsed childhood leukemia because affected children have few options and they hope to make a difference.

Based on progress to date, Dr. Lian was awarded new grants in 2018 and 2019 to fund additional years of this International Scholar grant. Based on progress to date, Dr. Lian was awarded a new grant in 2018 to fund an additional year of this International Scholar grant. MYCN-driven neuroblastoma accounts for about 30% of neuroblastomas and is associated with an extremely poor prognosis. Casein Kinase 2 (CK2) is an enzyme that is currently in clinical trials to treat multiple cancers. However, its efficacy on MYCN-driven neuroblastoma remains unknown. Dr. Lian's research aims to test if CK2 inhibition can serve as a new strategy to treat MYCN-driven neuroblastoma. A portion of this grant was named for The Amanda Rozman Pediatric Cancer Research Fund, a St. Baldrick's Hero Fund created in memory of Amanda Rozman and honors her courageous battle with neuroblastoma by funding promising new treatments and clinical trials in the area of translational research.

Based on progress to date, Dr. Wasswa was awarded new grants in 2018 and 2019 to fund additional years of this International Scholar grant. Whereas more than 80% of children with leukemia and lymphoma in the United States are cured with chemotherapy, in Africa a diagnosis with one of these diseases is an outright death sentence. To enable adaptation of chemotherapy protocols from the U.S. to treating children in Africa, Dr. Wasswa is studying the prevalent types of leukemia and lymphoma in children in Malawi and how their genetic code may affect response to chemotherapy.

Based on progress to date, Dr. Wasswa was awarded a new grant in 2018 to fund an additional year of this International Scholar grant. Whereas more than 80% of children with leukemia and lymphoma in the United States are cured with chemotherapy, in Africa a diagnosis with one of these diseases is an outright death sentence. To enable adaptation of chemotherapy protocols from the U.S. to treating children in Africa, Dr. Wasswa is studying the prevalent types of leukemia and lymphoma in children in Malawi and how their genetic code may affect response to chemotherapy.

Based on progress to date, Dr. Vasquez was awarded a new grant in 2017 to fund an additional year of this Fellow award. Dr. Vasquez, the Tap Cancer Out St. Baldrick's Fellow, is investigating the human immune system's response to pediatric brain tumors and how it can be manipulated in order to develop new treatments. Immune therapies can be highly specific for cancer cells because they target proteins only found on the cancer while sparing the normal cells. This research is using nanoparticles that contain the target protein as well as medications that block other cells that dampen the immune system in order to increase the immune system's ability to kill the cancer cells.

This grant recognizes the partnership with Tap Cancer Out, a jiu-jitsu based 501(c)(3) nonprofit raising awareness and funds for cancer fighting organizations on behalf of the grappling community.