Grants Search Results

This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant funds a Clinical Research Assistant to ensure that more kids can be treated on early-phase clinical trials, often their best hope for a cure.

This grant funds a Clinical Research Nurse who will also act as the Adolescent and Young Adult (AYA) Liaison to ensure that more kids, adolescents, and young adults can be treated on clinical trials, often their best hope for a cure.

This grant funds a Nurse Practitioner who enrolls and provides services for patients in the Childhood Cancer Survivorship Program. The program also provides critical patient data for survivorship researchers.

This grant funds a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant funds a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant supports construction of a REDCap database that will capture valuable clinical information on demographics, diagnosis, and treatment information for adolescent and young adult (AYA) cancer patients. The grant also supports a Patient Care Navigator who maintains the REDcap database and works to coordinate resources with other departments. This database helps track patients over time, giving more information to researchers and providing better long-term care for childhood cancer survivors.

This grant supports a Clinical Research Nurse to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant supports clinical research personnel to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant supports a Clinical Research Coordinator to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant funds the Nurse Researchers in the UIC/Rush/Stroger COG Program to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

The seeds of many childhood cancers are likely to be laid during human development before a child is born. Therefore, one may view childhood cancer cells as being stuck in development. Dr. Behjati aims to define at what stage tumour cells are stuck and to find ways of stimulating cancer cells to resume development. He envisions that this will provide a way of maturing cancer cells into harmless, non-cancerous cells. The St. Baldrick's Robert J. Arceci International Innovation Award is given in honor of the late Dr. Robert Arceci. A pioneer in the field, this award reflects Dr. Arceci's values including creativity, collaboration, and commitment to early- to mid-career scientists.

This grant supports the Defeat Pediatric Brain Tumors Research Collaborative, focused on helping kids with high-grade gliomas. The Collaborative is made up of four teams that study new targets for medicines, search brain cancer biomarkers, and conduct clinical trials, all to accelerate scientific discovery in pediatric brain tumors.

Based on progress to date, Dr. Parameswaran was awarded new grants in 2019 and 2020 to fund additional years of this Scholar grant. Acute Myeloid Leukemia (AML) is the second most common acute leukemia in children, and current treatment strategies are inadequate to cure AML. Dr. Parameswaran is developing a new strategy using Natural Killer cells, which are a type of white blood cells with potential to kill cancer cells. Cancer cells often produce a protein that makes Natural Killer cells less active, which helps the cancer cells escape from NK cell-mediated killing. Dr. Parameswaran and her team are developing methods to stop this NK cell inactivation and thereby improve NK cell function to treat pediatric AML.

This grant is generously supported by Rays of Hope, a St. Baldrick's Hero Fund created in memory of Rayanna Marrero. She was a happy 3 year old when she was diagnosed with Acute Lymphoblastic Leukemia. She battled ALL and won but a treatment induced secondary cancer claimed her life at age eight. Rayanna had an amazing attitude and loved life. She, like so many kids facing childhood cancer, did not allow it to define who she was. This Hero Fund aspires to give hope to kids fighting cancer through research.

Childhood brain tumors are frequently quite different than those of adults. Dr. Eck's For the Love of Jack St. Baldrick''s Research Grant aims to find new 'targeted' therapies for low-grade astrocytomas (a type of brain tumor) in children that are caused by a mutation in a protein called BRAF. BRAF mutations are common in cancer, and drugs have been developed that are effective in some tumors caused by one type of BRAF mutation. Unfortunately, these drugs do not work on the BRAF mutation found most often in pediatric brain tumors. Dr. Eck is using detailed information about the molecular structure of the BRAF mutation found in pediatric brain tumors to discover new drugs that specifically target this cause of brain tumors in children. Jack Tweedy was diagnosed with brain and spinal cancer when he was two. Since then he has endured multiple surgeries and 270 weeks of chemotherapy but never fails to uplift those around him. Together with his family, he inspires others to help fund the best research to ensure that all cancer warriors have better treatment options.

This institution is a member of a research consortium which is being funded by St. Baldrick's: Treehouse Childhood Cancer Initiative. For a description of this project, see the consortium grant made to the lead institution: University of California Santa Cruz, Santa Cruz, CA.

This institution is a member of a research consortium which is being funded by St. Baldrick's: Pediatric LEukemiA Precision-based Therapy (LEAP) Consortium. For a description of this project, see the consortium grant made to the lead institution: Dana-Farber Cancer Institute, Boston, MA.

Neuroblastoma is a common type of childhood cancer that arises from nerve-like cells and causes tumors just outside the brain. Dr. George is studying tumor cells from patients to discover new molecular targets for treatment of neuroblastoma. Dr. George and his team are growing tumor cells from patients and examining their electrical properties in order to identify specific proteins that carry electrical current that may be new targets for treating neuroblastoma using existing non-cancer drugs.

Based on progress to date, Dr. Llosa was awarded a new grant in 2019 to fund an additional year of this Scholar grant. Osteosarcoma is a tumor that forms in the bones and is the most common bone tumor of childhood. Dr. Llosa is investigating how the immune system interacts with cancer cells from osteosarcoma tumors. Dr. Llosa's focus is on immunotherapy, a type of cancer treatment designed to boost the body's natural defenses to fight the cancer, and one of the most promising current approaches for treating tumors. Immunotherapy uses materials either made by the body or in a laboratory to improve or restore immune system function with the final goal of stopping the growth of tumors. Dr. Llosa is studying the immune microenvironment of metastatic osteosarcomas to assess their potential for checkpoint blockade (where immune responses are allowed through an checkpoint in malignant cells in order to fight the cancer) as a therapeutic option.

This grant is made with generous support from the Ethan Jostad Foundation, established by Kim and Chris Jostad in 2011 in memory of their son, Ethan, who was taken by Alveolar Rhabdomyosarcoma at the age of nine. In addition to funding cutting-edge pediatric cancer research, the foundation's mission is to provide emotional and financial support to children and families impacted by the disease.