Grants Search Results

This grant develops, implements, and evaluates a novel curriculum in humanism and professionalism for pediatric oncology fellows. Funds will also be used to determine the optimal size of the pediatric hematology-oncology fellow workforce in order to meet the clinical demands of the field.

This grant funds a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant funds a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant helps provide necessary resources to build an early phase clinical trial program, and increase the number of such trial enrollments.

This grant funds a Research Assistant to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant funds a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

Funding from the St. Baldrick's Foundation has taken two very small programs at UIC and Rush Medical Centers, merged them and brought Stroger Medical Center into the fold to forge a single entity for purposes of participation in Children's Oncology Group clinical trials. This support of necessary personnel has significantly increased clinical trial participation for patients who otherwise might not have access to them.

This grant funds a Clinical Research Coordinator to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant funds a Research Nurse to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

Brain tumors are the most common solid cancer in children, and are often cured with radiation therapy. While radiation attacks the tumor, it can also leave the child with significant learning problems that affect their quality of life over the many years following cancer. Dr. Castellino focuses on understanding how heart function and brain vessel function may have been affected during treatment of the brain tumor. The goal of this research is to create strategies to prevent or lessen the injury to the brain during treatment, not only to cure the cancer in children, but also to preserve normal function for productive and healthy lives as cancer survivors.

Based on progress to date, Dr. Ladle was awarded a new grant in 2015 to fund an optional third year of this fellowship. While the body's immune system is capable of attacking cancer, many factors prevent this from happening. The goal of Dr. Ladle's research is to develop a vaccine to be given to patients that activates their own immune system to treat their cancer. The project focuses on how the body regulates the immune system to normally ignore cancer. New drugs are being developed that could help take the brakes off the immune system and allow it to recognize and attack cancer. Combining these drugs with a cancer vaccine could provide the boost needed for immune therapies to effectively treat pediatric cancers.

Based on progress to date, Dr. Schuback was awarded a new grant in 2015 to fund an optional third year of this fellowship. Dr. Schuback's research aims to improve treatment for children with Acute Myeloid Leukemia (AML), a type of blood cancer. This work focuses on characterizing the scope of mutations in a specific gene, ETV6, in children with AML. Preliminary work indicates that patients with such mutations are more likely to have a poor outcome. This project hopes to use the mutations in ETV6 as a marker to identify patients at high risk of relapse at the beginning of their treatment, in order to predetermine therapies that are most likely to succeed.

Based on progress to date, Dr. Barth was awarded new grants in 2016 and 2017 to fund additional years of this Scholar award. Children with B-cell non-Hodgkins lymphoma (B-NHL) whose disease is resistant to initial therapies have a dismal outcome. As the Do It For Dominic St. Baldrick's Scholar, Dr. Barth and his team have identified alterations in lymphoma cells that contribute to therapy resistance. This study investigates the ability to reverse or overcome resistance by targeting these altered pathways using targeted inhibitors. By inhibiting these pathways, he hopes to kill resistant lymphoma cells or re-sensitize resistant cells to traditional chemotherapy, potentially providing new future treatment options for patients with an otherwise poor prognosis.

This grant is named for the Do It for Dominic Fund which honors the memory of Dominic Cairo who battled non-Hodgkins lymphoma and was a hero to his school and community. His family and friends continue to raise funds and support research in the hopes that no child has to go through what Dominic endured.

Nutrition experts recommend that pediatric cancer survivors eat more fruits, vegetables, and whole grain products, and to lead active lifestyles. However, studies suggest that childhood cancer survivors are at risk for excessive weight gain and poor fitness. Strategies to enhance the nutritional quality of diets and to promote physical activity among cancer survivors are greatly needed. This study assesses the feasibility of healthy lifestyle coaching by group televideo conferencing to encourage healthy lifestyle modifications.

Medulloblastoma is the most common malignant brain tumor. There is an urgent need to develop novel therapies for children with medulloblastoma. Dr. Van Meir and his team are studying the importance of the loss of tumor suppressor BAI1 in medulloblastoma. Such new knowledge has the potential to reveal new ways to treat this disease.

Despite the toxic effects of current treatment for children and young adults with AML, overall survival remains poor because of recurrent leukemia. If their AML does not respond to chemotherapy after relapse, chances for survival are low. This team has identified important changes in AML that can be exploited to develop more effective and less toxic treatments using new types of drugs. The consortium focuses on showing that these pathways are needed for leukemia survival, and developing pathway-directed clinical trials to improve outcomes for this group of patients with no other treatment options. Awarded to Phoenix Children's Hospital and transferred to Fred Hutchinson Cancer Research Center. Funds administered by Fred Hutchinson Cancer Research Center.

This institution is a member of a research consortium which is being funded by St. Baldrick's: PBMTC Late Effects Consortium. For a description of this project, see the consortium grant made to the lead institution: Dana-Farber Cancer Institute, Boston, MA.

This institution is a member of a research consortium which is being funded by St. Baldrick's: PBMTC Late Effects Consortium. For a description of this project, see the consortium grant made to the lead institution: Dana-Farber Cancer Institute, Boston, MA.

This institution is a member of a research consortium which is being funded by St. Baldrick's: PBMTC Late Effects Consortium. For a description of this project, see the consortium grant made to the lead institution: Dana-Farber Cancer Institute, Boston, MA.

This institution is a member of a research consortium which is being funded by St. Baldrick's: PBMTC Late Effects Consortium. For a description of this project, see the consortium grant made to the lead institution: Dana-Farber Cancer Institute, Boston, MA.