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Showing 481-500 of 2390 results

Ramon Sun Ph.D.

Researcher Photo

Funded: 08-01-2019 through 07-31-2022
Funding Type: St. Baldrick's Scholar
Institution Location: Lexington, KY
Institution: University of Kentucky Research Foundation affiliated with Kentucky Children's Hospital

In the new era of personalized medicine, Ewing sarcoma still relies on decades-old chemotherapy options, where aggressive treatments are met with poor disease outcomes. Ewing sarcoma is a devastating disease that affects children and young adults age 5-16. Based on treatment outcome and patient qualities of life, Ewing sarcoma is in desperate need of research and development of new therapeutic options. One of the key observations of Ewing sarcoma made back in the 1930s is the accumulation of a large amount of glycogen. Glycogen is a sugar molecule that our body uses to store energy; only specific organs such as the liver and muscle are capable of producing glycogen. The ability of Ewing sarcoma tumors to store large amount of glycogen has been forgotten until now. Dr. Sun aims to understand the reason behind large glycogen accumulation in Ewing sarcoma and exploit the glycogen deposits as a possible drug target for the treatment of Ewing sarcoma. The successful completion of this project will bring new hope to this century-old disease and facilitate the development of the next generation of novel therapeutics specifically for Ewing sarcoma.

A portion of this grant is funded by and named for Julia's Legacy of Hope, a St. Baldrick's Hero Fund that honors her positive and courageous spirit and carries out Julia's last wish: "no child should have to go through what I have experienced". Diagnosed at age 16 with Ewing sarcoma, Julia fought cancer and survived only to be stricken in college with acute myeloid leukemia, a secondary cancer as a result of treatment. Through this Hero Fund, her family hopes to raise awareness and funds for childhood cancer research especially for Adolescent and Young Adult (AYA) patients.

Cleveland Clinic Foundation Summer Fellow

Researcher Photo

Funded: 08-01-2019 through 10-31-2019
Funding Type: St. Baldrick's Summer Fellow
Institution Location: Cleveland, OH
Institution: Cleveland Clinic Children's Hospital affiliated with The Cleveland Clinic Lerner College of Medicine

This grant funds a medical school student to complete work in pediatric oncology research for the summer. The experience may encourage them to choose childhood cancer research as a specialty. Therapies that stimulate the immune system to target cancer cells are rapidly providing new and efficacious treatment options for pediatric patients with cancer. However, scientists are finding that solid tumors have evolved methods of inhibiting the immune system, minimizing the effects of these new therapies. One way of suppressing the immune system is through the upregulation of myeloid-derived suppressor cells. This study will help determine the prevalence and function of these cells in pediatric patients with solid tumors so that they can be specifically targeted to improve the efficacy of new immunotherapies.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Bethesda, MD
Institution: Walter Reed National Military Medical Center

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Nashville, TN
Institution: Vanderbilt University Medical Center affiliated with Monroe Carell Jr. Children's Hospital at Vanderbilt

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Dallas, TX
Institution: University of Texas Southwestern Medical Center at Dallas

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Madison, WI
Institution: University of Wisconsin-Madison affiliated with American Family Children's Hospital

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Salt Lake City, UT
Institution: University of Utah affiliated with Huntsman Cancer Institute

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Louisville, KY
Institution: University of Louisville affiliated with Kosair Children's Hospital, Norton Healthcare

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Lexington, KY
Institution: University of Kentucky Research Foundation affiliated with Kentucky Children's Hospital

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Honolulu, HI
Institution: Tripler Army Medical Center

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Lubbock, TX
Institution: Texas Tech University Health Sciences Center

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: West Palm Beach, FL
Institution: Palm Beach Children's Hospital at St. Mary's Medical Center

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Louisville, KY
Institution: Kosair Children's Hospital, Norton Healthcare affiliated with University of Louisville

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Macon, GA
Institution: Beverly Knight Olson Children's Hospital Navicent Health

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Portsmouth, VA
Institution: Naval Medical Center, Portsmouth

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Bethlehem, PA
Institution: Lehigh Valley Health Network affiliated with Lehigh Valley Hospital

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Baltimore, MD
Institution: Johns Hopkins Children's Center affiliated with Johns Hopkins University School of Medicine

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Ft. Worth, TX
Institution: Cook Children's Medical Center

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Bronx, NY
Institution: Children's Hospital at Montefiore affiliated with Albert Einstein College of Medicine of Yeshiva University, Montefiore Medical Center

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.

North American Consortium for Histiocytosis (NACHO) Member

Funded: 07-01-2019 through 06-30-2025
Funding Type: Consortium Research Grant
Institution Location: Richmond, VA
Institution: Children's Hospital of Richmond at VCU affiliated with Virginia Commonwealth University

This institution is a member of a research consortium which is being funded by St. Baldrick's: North American Consortium for Histiocytosis (NACHO). For a description of this project, see the consortium grant made to the lead institution: St. Jude Children's Research Hospital, Memphis, TN.