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Ewing sarcoma is a deadly cancer that affects children and young adults. Dr. Gao and team know that these cancer cells depend on a special protein, ETV6, to stay alive. Certain natural fats inside the cell can weaken this protein and slow the cancer's growth. Dr. Gao and colleagues will learn exactly how these fats affect the cancer cells and will search for medicines that safely increase these fats to damage the tumor. Dr. Gao's research will open the door to new and gentler treatment options for children with Ewing sarcoma.