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The causes of relapse of acute lymphocytic leukemia (ALL) remain unknown and there are limited therapies for such children. Dr. Licht characterized a mutation of a gene present in 10-20% of children with relapsed ALL. A mutation in this gene that may cause relapse by reprograming cells to grow more rapidly and become chemotherapy-resistant. Using a new technique Dr. Licht's Do It for Dominic St. Baldrick’s Research Grant aims to determine how the mutation increases growth and causes drug resistance in order to devise new therapies for relapsed ALL.

The grant is named for the Do It for Dominic Hero Fund created in memory of Dominic Cairo. His family and friends continue to raise funds and support St. Baldrick’s to find cures for childhood cancers so no child ever has to go through what Dominic had to endure.