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Better therapies that specifically target cancer cells while leaving normal cells undamaged will lead to therapies with fewer short or long term side effects. Cancer, specifically Ewing sarcoma, changes how proteins are made. New proteins occur by rearranging the messages that come from DNA. The rearranged messages turn into proteins that keep the cancer growing. Dr. Toretsky's research aims to find out what the rearranged messages are and how the new proteins could be targeted with new medicines.

This grant is made with generous support from the Team Clarkie Fund, a St. Baldrick's Hero Fund created to honor Clarkie Carroll. It will fund Ewing sarcoma research while stimulating greater awareness and inspiring others to believe pediatric cancer research can and will lead to a cure.