Based on progress to date, Dr. Allen-Rhoades was awarded a new grant in 2014 to fund an optional third year of this fellowship. Osteosarcoma is a bone cancer that affects children, adolescents and young adults. Patients have better survival if the cancer has not spread to other parts of the body. This project aims to develop a blood test that can detect the cancer and determine if it has spread to other areas. This test will be more sensitive and easier to use than current methods, and will ultimately help improve the survival of children with osteosarcoma.