Based on progress to date, Dr. Pinkney was awarded a new grant in 2014 to fund an optional third year of this fellowship. Kerice Pinkney, M.B.B.S., Gen Re St. Baldrick's Fellow, studies ATM, a protein that regulates the response of a cell when DNA is damaged. Mutation of ATM leads to increased breaks in DNA. This can then lead to chromosomal translocation, a process by which pieces of chromosomes are swapped. This can cause normal genes to combine together and lead to a new gene that can induce cancer. The goal of this project is to study how the protein ATM suppresses the translocation of chromosomes and therefore better understand the cause of pediatric cancers. This grant is named for the General Reinsurance (Gen Re) team, which has raised more than $1 million to date for lifesaving research through the St. Baldrick's Foundation. Awarded at Columbia University and transferred to Joe DiMaggio Children's Hospital.