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Joseph Lubega M.D.

Researcher Photo

Funded: 07-01-2013 through 06-30-2019
Funding Type: International Scholar
Institution Location: Kampala, Uganda
Institution: Uganda Cancer Institute

Based on progress to date, Dr. Lubega was awarded new grants in 2016 and 2017 to fund additional years of this International Scholar award. A third of cancers in children in Africa are due to Burkitt's lymphoma. Burkitt's lymphoma seems to arise from the body's attempt to fight Epstein-Barr virus and malaria infections. This study measures infection-fighting proteins in children with and without Burkitt's lymphoma. The goal is to discover if these infection-fighting proteins in blood or saliva can be used as specific indicators of Burkitt's lymphoma. These proteins can be developed into clinical tests for early detection and monitoring treatment for children with cancer.

Soad Fuentes Alabi M.D.

Researcher Photo

Funded: 07-01-2013 through 08-31-2018
Funding Type: International Scholar
Institution Location: San Salvador, El Salvador
Institution: Hospital Nacional de Niños Benjamin Bloom

Based on progress to date, Dr. Fuentes Alabi was awarded new grants in 2016 and 2017 to fund additional years of this International Scholar award. The majority of children with cancer live in countries with limited resources and yet we know very little about the types of pediatric cancer and their distribution in those settings. Studies suggest that the incidence of some types of childhood cancer is not the same among different ethnic and socioeconomic groups. Epidemiology studies focused on those unique areas of the world are very important because they can help improve our overall understanding of childhood cancers. This project aims to build epidemiology research capacity in Central America through the training of Dr. Fuentes Alabi.

SUNY Upstate Summer Fellow

Funded: 06-10-2013 through 04-30-2014
Funding Type: St. Baldrick's Summer Fellow
Institution Location: Syracuse, NY
Institution: SUNY Upstate Medical University affiliated with Golisano Children's Hospital, Syracuse

This grant funds a first year medical student to work in a pediatric oncology research lab for the summer. The experience may encourage them to choose childhood cancer research as a specialty.

Cornell University Summer Fellow

Funded: 06-07-2013 through 08-02-2013
Funding Type: St. Baldrick's Summer Fellow
Institution Location: New York, NY
Institution: Weill Medical College of Cornell University affiliated with Weill Cornell Medical Center, New York-Presbyterian

This grant funds a first year medical student to work in a pediatric oncology research lab for the summer. The experience may encourage them to choose childhood cancer research as a specialty.

University of Colorado Denver Summer Fellow

Funded: 06-03-2013 through 08-09-2013
Funding Type: St. Baldrick's Summer Fellow
Institution Location: Denver, CO
Institution: University of Colorado affiliated with Children's Hospital Colorado

This grant funds a first year medical student to work in a pediatric oncology research lab for the summer. The experience may encourage them to choose childhood cancer research as a specialty.

University of Kansas Summer Fellow

Funded: 06-03-2013 through 07-31-2013
Funding Type: St. Baldrick's Summer Fellow
Institution Location: Kansas City, KS
Institution: University of Kansas Medical Center

This grant funds a first year medical student to work in a pediatric oncology research lab for the summer. The experience may encourage them to choose childhood cancer research as a specialty.

St. Baldrick's Foundation Empowering Pediatric Immunotherapies for Childhood Cancer Team (SBF-EPICC Team)

Funded: 06-01-2013 through 05-31-2025
Funding Type: Consortium Research Grant
Institution Location: Houston, TX
Institution: Baylor College of Medicine affiliated with Vannie E. Cook Jr. Children's Cancer and Hematology Clinic, Texas Children's Hospital

Immunotherapy is an exceedingly promising approach to transform the way we treat childhood cancers, increasing cures while decreasing toxicity. The St. Baldrick's Foundation EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer) brings together experts from the fields of genomics and immunotherapy from across North America. This team is developing new, targeted immunotherapies for the most difficult to cure childhood cancers. Discoveries are made through basic, translational, and clinical studies conducted in parallel, catalyzing progress in each sphere. The goals are to discover molecules on pediatric cancers that are targetable using immunotherapies, and to develop new therapeutics to target children's cancers. This focus is complementary with other genomic and immunotherapy consortia. The SBF-EPICC team conducts early phase clinical trials of promising immunotherapies throughout North America with a focus on understanding mechanisms of resistance to current approaches as a first step toward developing next generation therapeutics. The team is made up of researchers at ten institutions: Baylor College of Medicine, British Columbia Cancer Agency, Children's Hospital of Philadelphia, Hospital for Sick Children, National Cancer Institute, Seattle Children's Hospital, Stanford University, University of Colorado Denver, University of Pittsburgh, and University of Wisconsin. Funds administered by The Children's Hospital of Philadelphia. This team began in 2013 as the Stand Up To Cancer-St. Baldrick's Foundation Pediatric Cancer Dream Team. In 2022, the work continues as the St. Baldrick's EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer Team), with continued funding from St. Baldrick's and funding partners.

St. Baldrick's Foundation Empowering Pediatric Immunotherapies for Childhood Cancer Team (SBF-EPICC Team)

Funded: 06-01-2013 through 05-31-2025
Funding Type: Consortium Research Grant
Institution Location: Vancouver, BC
Institution: British Columbia Cancer Agency affiliated with British Columbia Children's Hospital, The University of British Columbia

Immunotherapy is an exceedingly promising approach to transform the way we treat childhood cancers, increasing cures while decreasing toxicity. The St. Baldrick's Foundation EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer) brings together experts from the fields of genomics and immunotherapy from across North America. This team is developing new, targeted immunotherapies for the most difficult to cure childhood cancers. Discoveries are made through basic, translational, and clinical studies conducted in parallel, catalyzing progress in each sphere. The goals are to discover molecules on pediatric cancers that are targetable using immunotherapies, and to develop new therapeutics to target children's cancers. This focus is complementary with other genomic and immunotherapy consortia. The SBF-EPICC team conducts early phase clinical trials of promising immunotherapies throughout North America with a focus on understanding mechanisms of resistance to current approaches as a first step toward developing next generation therapeutics. The team is made up of researchers at ten institutions: Baylor College of Medicine, British Columbia Cancer Agency, Children's Hospital of Philadelphia, Hospital for Sick Children, National Cancer Institute, Seattle Children's Hospital, Stanford University, University of Colorado Denver, University of Pittsburgh, and University of Wisconsin. Funds administered by The Children's Hospital of Philadelphia. This team began in 2013 as the Stand Up To Cancer-St. Baldrick's Foundation Pediatric Cancer Dream Team. In 2022, the work continues as the St. Baldrick's EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer Team), with continued funding from St. Baldrick's and funding partners.

St. Baldrick's Foundation Empowering Pediatric Immunotherapies for Childhood Cancer Team (SBF-EPICC Team)

Funded: 06-01-2013 through 05-31-2025
Funding Type: Consortium Research Grant
Institution Location: Philadelphia, PA
Institution: The Children's Hospital of Philadelphia affiliated with University of Pennsylvania

Immunotherapy is an exceedingly promising approach to transform the way we treat childhood cancers, increasing cures while decreasing toxicity. The St. Baldrick's Foundation EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer) brings together experts from the fields of genomics and immunotherapy from across North America. This team is developing new, targeted immunotherapies for the most difficult to cure childhood cancers. Discoveries are made through basic, translational, and clinical studies conducted in parallel, catalyzing progress in each sphere. The goals are to discover molecules on pediatric cancers that are targetable using immunotherapies, and to develop new therapeutics to target children's cancers. This focus is complementary with other genomic and immunotherapy consortia. The SBF-EPICC team conducts early phase clinical trials of promising immunotherapies throughout North America with a focus on understanding mechanisms of resistance to current approaches as a first step toward developing next generation therapeutics. The team is made up of researchers at ten institutions: Baylor College of Medicine, British Columbia Cancer Agency, Children's Hospital of Philadelphia, Hospital for Sick Children, National Cancer Institute, Seattle Children's Hospital, Stanford University, University of Colorado Denver, University of Pittsburgh, and University of Wisconsin. Funds administered by The Children's Hospital of Philadelphia. This team began in 2013 as the Stand Up To Cancer-St. Baldrick's Foundation Pediatric Cancer Dream Team. In 2022, the work continues as the St. Baldrick's EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer Team), with continued funding from St. Baldrick's and funding partners.

St. Baldrick's Foundation Empowering Pediatric Immunotherapies for Childhood Cancer Team (SBF-EPICC Team)

Funded: 06-01-2013 through 05-31-2025
Funding Type: Consortium Research Grant
Institution Location: Toronto, ON
Institution: Hospital for Sick Children

Immunotherapy is an exceedingly promising approach to transform the way we treat childhood cancers, increasing cures while decreasing toxicity. The St. Baldrick's Foundation EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer) brings together experts from the fields of genomics and immunotherapy from across North America. This team is developing new, targeted immunotherapies for the most difficult to cure childhood cancers. Discoveries are made through basic, translational, and clinical studies conducted in parallel, catalyzing progress in each sphere. The goals are to discover molecules on pediatric cancers that are targetable using immunotherapies, and to develop new therapeutics to target children's cancers. This focus is complementary with other genomic and immunotherapy consortia. The SBF-EPICC team conducts early phase clinical trials of promising immunotherapies throughout North America with a focus on understanding mechanisms of resistance to current approaches as a first step toward developing next generation therapeutics. The team is made up of researchers at ten institutions: Baylor College of Medicine, British Columbia Cancer Agency, Children's Hospital of Philadelphia, Hospital for Sick Children, National Cancer Institute, Seattle Children's Hospital, Stanford University, University of Colorado Denver, University of Pittsburgh, and University of Wisconsin. Funds administered by The Children's Hospital of Philadelphia. This team began in 2013 as the Stand Up To Cancer-St. Baldrick's Foundation Pediatric Cancer Dream Team. In 2022, the work continues as the St. Baldrick's EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer Team), with continued funding from St. Baldrick's and funding partners.

St. Baldrick's Foundation Empowering Pediatric Immunotherapies for Childhood Cancer Team (SBF-EPICC Team)

Funded: 06-01-2013 through 05-31-2025
Funding Type: Consortium Research Grant
Institution Location: Bethesda, MD
Institution: National Cancer Institute, National Institutes of Health affiliated with NIH Clinical Center

Immunotherapy is an exceedingly promising approach to transform the way we treat childhood cancers, increasing cures while decreasing toxicity. The St. Baldrick's Foundation EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer) brings together experts from the fields of genomics and immunotherapy from across North America. This team is developing new, targeted immunotherapies for the most difficult to cure childhood cancers. Discoveries are made through basic, translational, and clinical studies conducted in parallel, catalyzing progress in each sphere. The goals are to discover molecules on pediatric cancers that are targetable using immunotherapies, and to develop new therapeutics to target children's cancers. This focus is complementary with other genomic and immunotherapy consortia. The SBF-EPICC team conducts early phase clinical trials of promising immunotherapies throughout North America with a focus on understanding mechanisms of resistance to current approaches as a first step toward developing next generation therapeutics. The team is made up of researchers at ten institutions: Baylor College of Medicine, British Columbia Cancer Agency, Children's Hospital of Philadelphia, Hospital for Sick Children, National Cancer Institute, Seattle Children's Hospital, Stanford University, University of Colorado Denver, University of Pittsburgh, and University of Wisconsin. Funds administered by The Children's Hospital of Philadelphia. This team began in 2013 as the Stand Up To Cancer-St. Baldrick's Foundation Pediatric Cancer Dream Team. In 2022, the work continues as the St. Baldrick's EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer Team), with continued funding from St. Baldrick's and funding partners.

St. Baldrick's Foundation Empowering Pediatric Immunotherapies for Childhood Cancer Team (SBF-EPICC Team)

Funded: 06-01-2013 through 05-31-2025
Funding Type: Consortium Research Grant
Institution Location: Seattle, WA
Institution: Seattle Children's Hospital affiliated with Fred Hutchinson Cancer Research Center, University of Washington

Immunotherapy is an exceedingly promising approach to transform the way we treat childhood cancers, increasing cures while decreasing toxicity. The St. Baldrick's Foundation EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer) brings together experts from the fields of genomics and immunotherapy from across North America. This team is developing new, targeted immunotherapies for the most difficult to cure childhood cancers. Discoveries are made through basic, translational, and clinical studies conducted in parallel, catalyzing progress in each sphere. The goals are to discover molecules on pediatric cancers that are targetable using immunotherapies, and to develop new therapeutics to target children's cancers. This focus is complementary with other genomic and immunotherapy consortia. The SBF-EPICC team conducts early phase clinical trials of promising immunotherapies throughout North America with a focus on understanding mechanisms of resistance to current approaches as a first step toward developing next generation therapeutics. The team is made up of researchers at ten institutions: Baylor College of Medicine, British Columbia Cancer Agency, Children's Hospital of Philadelphia, Hospital for Sick Children, National Cancer Institute, Seattle Children's Hospital, Stanford University, University of Colorado Denver, University of Pittsburgh, and University of Wisconsin. Funds administered by The Children's Hospital of Philadelphia. This team began in 2013 as the Stand Up To Cancer-St. Baldrick's Foundation Pediatric Cancer Dream Team. In 2022, the work continues as the St. Baldrick's EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer Team), with continued funding from St. Baldrick's and funding partners.

St. Baldrick's Foundation Empowering Pediatric Immunotherapies for Childhood Cancer Team (SBF-EPICC Team)

Funded: 06-01-2013 through 05-31-2025
Funding Type: Consortium Research Grant
Institution Location: Palo Alto, CA
Institution: Stanford University affiliated with Lucile Packard Children’s Hospital

Immunotherapy is an exceedingly promising approach to transform the way we treat childhood cancers, increasing cures while decreasing toxicity. The St. Baldrick's Foundation EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer) brings together experts from the fields of genomics and immunotherapy from across North America. This team is developing new, targeted immunotherapies for the most difficult to cure childhood cancers. Discoveries are made through basic, translational, and clinical studies conducted in parallel, catalyzing progress in each sphere. The goals are to discover molecules on pediatric cancers that are targetable using immunotherapies, and to develop new therapeutics to target children's cancers. This focus is complementary with other genomic and immunotherapy consortia. The SBF-EPICC team conducts early phase clinical trials of promising immunotherapies throughout North America with a focus on understanding mechanisms of resistance to current approaches as a first step toward developing next generation therapeutics. The team is made up of researchers at ten institutions: Baylor College of Medicine, British Columbia Cancer Agency, Children's Hospital of Philadelphia, Hospital for Sick Children, National Cancer Institute, Seattle Children's Hospital, Stanford University, University of Colorado Denver, University of Pittsburgh, and University of Wisconsin. Funds administered by The Children's Hospital of Philadelphia. This team began in 2013 as the Stand Up To Cancer-St. Baldrick's Foundation Pediatric Cancer Dream Team. In 2022, the work continues as the St. Baldrick's EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer Team), with continued funding from St. Baldrick's and funding partners. Pediatric brain tumors are the leading cause of cancer-related deaths in children, and atypical teratoid/rhabdoid tumors (ATRT) are among the most aggressive, with a dismal prognosis. Moreover, treatment related toxicities of current standard therapies cause long term health issues. Researchers at Stanford University, as part of the Stand Up To Cancer-St. Baldrick's Foundation Pediatric Cancer Dream Team, recently discovered that 100% of ATRT tumors express a protein called B7-H3 and demonstrated that this can be a novel target for cancer immunotherapy. Chimeric Antigen Receptor (CAR) T cells targeting B7-H3 demonstrated dramatic responses against preclinical models of ATRT. They further demonstrated that CAR T cells administered into the central nervous system were more potent and less toxic than systemically administered CAR T cells. This therapy has the potential to dramatically alter outcome for children with these aggressive cancers, and researchers are working towards translating the recent findings into the clinic. A portion of this project is generously supported by Hope4ATRT, a St. Baldrick's charity partner. Zion Yamoah was diagnosed with an aggressive brain tumor called AT/RT just before his third birthday and passed away 15 months later. His love of music and his bright spirit inspired his parents to establish Hope4ATRT. Its mission is to raise funds for innovative research specifically targeted for AT/RT while also helping families to navigate available treatment options and current research in the field. A portion of this project is generously supported by Bianka's Butterfly Fund for PNET Brain Tumor Research, a St. Baldrick's Hero Fund. Four-year old Bianka Kucelin was diagnosed with a malignant brain cancer known as PNET. Despite extensive treatment, the little girl who loved butterflies passed away in May 2015. Bianka will be remembered for her joyful spirit and courageous grace. This Hero Fund honors her life and aspires to fund PNET research grants.

St. Baldrick's Foundation Empowering Pediatric Immunotherapies for Childhood Cancer Team (SBF-EPICC Team)

Funded: 06-01-2013 through 05-31-2025
Funding Type: Consortium Research Grant
Institution Location: Denver, CO
Institution: University of Colorado affiliated with Children's Hospital Colorado

Immunotherapy is an exceedingly promising approach to transform the way we treat childhood cancers, increasing cures while decreasing toxicity. The St. Baldrick's Foundation EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer) brings together experts from the fields of genomics and immunotherapy from across North America. This team is developing new, targeted immunotherapies for the most difficult to cure childhood cancers. Discoveries are made through basic, translational, and clinical studies conducted in parallel, catalyzing progress in each sphere. The goals are to discover molecules on pediatric cancers that are targetable using immunotherapies, and to develop new therapeutics to target children's cancers. This focus is complementary with other genomic and immunotherapy consortia. The SBF-EPICC team conducts early phase clinical trials of promising immunotherapies throughout North America with a focus on understanding mechanisms of resistance to current approaches as a first step toward developing next generation therapeutics. The team is made up of researchers at ten institutions: Baylor College of Medicine, British Columbia Cancer Agency, Children's Hospital of Philadelphia, Hospital for Sick Children, National Cancer Institute, Seattle Children's Hospital, Stanford University, University of Colorado Denver, University of Pittsburgh, and University of Wisconsin. Funds administered by The Children's Hospital of Philadelphia. This team began in 2013 as the Stand Up To Cancer-St. Baldrick's Foundation Pediatric Cancer Dream Team. In 2022, the work continues as the St. Baldrick's EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer Team), with continued funding from St. Baldrick's and funding partners.

St. Baldrick's Foundation Empowering Pediatric Immunotherapies for Childhood Cancer Team (SBF-EPICC Team)

Funded: 06-01-2013 through 05-31-2025
Funding Type: Consortium Research Grant
Institution Location: Pittsburgh, PA
Institution: University of Pittsburgh affiliated with Children's Hospital of Pittsburgh

Immunotherapy is an exceedingly promising approach to transform the way we treat childhood cancers, increasing cures while decreasing toxicity. The St. Baldrick's Foundation EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer) brings together experts from the fields of genomics and immunotherapy from across North America. This team is developing new, targeted immunotherapies for the most difficult to cure childhood cancers. Discoveries are made through basic, translational, and clinical studies conducted in parallel, catalyzing progress in each sphere. The goals are to discover molecules on pediatric cancers that are targetable using immunotherapies, and to develop new therapeutics to target children's cancers. This focus is complementary with other genomic and immunotherapy consortia. The SBF-EPICC team conducts early phase clinical trials of promising immunotherapies throughout North America with a focus on understanding mechanisms of resistance to current approaches as a first step toward developing next generation therapeutics. The team is made up of researchers at ten institutions: Baylor College of Medicine, British Columbia Cancer Agency, Children's Hospital of Philadelphia, Hospital for Sick Children, National Cancer Institute, Seattle Children's Hospital, Stanford University, University of Colorado Denver, University of Pittsburgh, and University of Wisconsin. Funds administered by The Children's Hospital of Philadelphia. This team began in 2013 as the Stand Up To Cancer-St. Baldrick's Foundation Pediatric Cancer Dream Team. In 2022, the work continues as the St. Baldrick's EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer Team), with continued funding from St. Baldrick's and funding partners.

St. Baldrick's Foundation Empowering Pediatric Immunotherapies for Childhood Cancer Team (SBF-EPICC Team)

Funded: 06-01-2013 through 05-31-2025
Funding Type: Consortium Research Grant
Institution Location: Madison, WI
Institution: University of Wisconsin-Madison affiliated with American Family Children's Hospital

Immunotherapy is an exceedingly promising approach to transform the way we treat childhood cancers, increasing cures while decreasing toxicity. The St. Baldrick's Foundation EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer) brings together experts from the fields of genomics and immunotherapy from across North America. This team is developing new, targeted immunotherapies for the most difficult to cure childhood cancers. Discoveries are made through basic, translational, and clinical studies conducted in parallel, catalyzing progress in each sphere. The goals are to discover molecules on pediatric cancers that are targetable using immunotherapies, and to develop new therapeutics to target children's cancers. This focus is complementary with other genomic and immunotherapy consortia. The SBF-EPICC team conducts early phase clinical trials of promising immunotherapies throughout North America with a focus on understanding mechanisms of resistance to current approaches as a first step toward developing next generation therapeutics. The team is made up of researchers at ten institutions: Baylor College of Medicine, British Columbia Cancer Agency, Children's Hospital of Philadelphia, Hospital for Sick Children, National Cancer Institute, Seattle Children's Hospital, Stanford University, University of Colorado Denver, University of Pittsburgh, and University of Wisconsin. Funds administered by The Children's Hospital of Philadelphia. This team began in 2013 as the Stand Up To Cancer-St. Baldrick's Foundation Pediatric Cancer Dream Team. In 2022, the work continues as the St. Baldrick's EPICC Team (Empowering Pediatric Immunotherapies for Childhood Cancer Team), with continued funding from St. Baldrick's and funding partners.

Children's Hospital Los Angeles Summer Fellow

Funded: 04-01-2013 through 08-31-2013
Funding Type: St. Baldrick's Summer Fellow
Institution Location: Los Angeles, CA
Institution: Children's Hospital Los Angeles

This grant funds a first year medical student to work in a pediatric oncology research lab for the summer. The experience may encourage them to choose childhood cancer research as a specialty.

UCSF Summer Fellow

Funded: 04-01-2013 through 08-31-2013
Funding Type: St. Baldrick's Summer Fellow
Institution Location: San Francisco, CA
Institution: University of California, San Francisco affiliated with UCSF Benioff Children's Hospital

This grant funds a first year medical student to work in a pediatric oncology research lab for the summer. The experience may encourage them to choose childhood cancer research as a specialty.

Georgetown University Summer Fellow

Funded: 04-01-2013 through 08-31-2013
Funding Type: St. Baldrick's Summer Fellow
Institution Location: Washington, DC
Institution: Georgetown University affiliated with MedStar Georgetown University Hospital

This grant funds a first year medical student to work in a pediatric oncology research lab for the summer. The experience may encourage them to choose childhood cancer research as a specialty.

University of Hawaii Summer Fellow

Funded: 04-01-2013 through 08-31-2013
Funding Type: St. Baldrick's Summer Fellow
Institution Location: Honolulu, HI
Institution: University of Hawaii Cancer Center

This grant funds a first year medical student to work in a pediatric oncology research lab for the summer. The experience may encourage them to choose childhood cancer research as a specialty.