Grants Search Results

This grant funds a student to complete work in pediatric oncology research for the summer. Two highly aggressive brain tumors, Atypical Teratoid/Rhabdoid Tumors and Embryonal Tumor with Multilayered Rosettes have extremely low survival rates. These tumors arise from a change in normal brain cells that cause uncontrollable growth and tumor development. Inhibiting specific pathways that are important in tumor growth will prevent the tumor development. To test this hypothesis, the team will perform multiple tests using cells from patients tumor cells growing in the lab. Testing how healthy the cells are, how they grow in their life cycle, and how they respond to being treated with a drug. Further, looking at specific proteins a part of these tumors and how they can help inform treatment for patients. These results may lead to a possible early-stage treatment option for patients affected by these cancers. This work is being completed under the mentorship of Dr. Giselle Saulnier Sholler.

This grant funds a student to complete work in pediatric oncology research for the summer. Neuroblastoma is a pediatric cancer that develops in immature nerve cells and accounts for 15% of cancer-associated deaths among children. The Feng laboratory has recently reported that MYCN-driven cancers secrete a signaling molecule to hijack the body's immune system to promote tumor development and aggressiveness. This proposal seeks to characterize whether this signaling molecule explores macrophages, a type immune cells, to foster the development of MYCN-driven neuroblastoma. Successful completion of this research will help researchers understand the crosstalk between the tumor and immune cells and may identify new therapeutic strategy to treat high-risk neuroblastoma and other MYCN-driven childhood cancers such as medulloblastoma and glioma. This work is being completed under the mentorship of Dr. Hui Feng.

This grant funds a student to complete work in pediatric oncology research for the summer. Pediatric sarcomas are devastating childhood cancers. New therapies that have fewer side effects but can more effectively kill cancer cells are urgently needed. There are multiple factors that make pediatric sarcomas hard to treat. One of those reasons is that not all pediatric sarcoma cells are like each other. Some grow very fast, whereas some others grow more slowly but can migrate and form metastases. Dr. Langdon's laboratory is working on developing combination therapies that can limit the impact of all the different types of pediatric sarcoma cells. During the next summer, the St. Baldrick's Foundation Summer Fellow's project will be to discover reasons why these combinations work so well against pediatric sarcoma cells. They will also learn several new techniques and gain experience in mentoring and more effective communication strategies. This work is being completed under the mentorship of Dr. Casey Langdon.

Many patients treated at the Children's Hospital of Michigan Foundation are of minority background, and historically minority patients have not had the same access to health care or medical research. This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

El Paso Children's Hospital is the sole provider of pediatric cancer care and clinical trials in the El Paso region, serving a predominantly Hispanic, underserved population. Positioned on the Mexico border, the hospital addresses a critical need for specialized cancer care among Hispanic children, who often face more aggressive cancers and poorer outcomes due to genetic factors and limited access to clinical trials. Since opening in 2012, the hospital has become a key player in pediatric oncology, supported by Texas Tech University Health Sciences Center El Paso Paul L. Foster School of Medicine. Membership in the Children’s Oncology Group (COG) since 2014 has allowed Dr. Carcamo and colleagues to offer cutting-edge therapeutic protocols and comprehensive care through research collaboration. This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

Through the HSHS Wisconsin Clinical Research Institute, children have access to cancer research trials at a location close to home. This grant supports Clinical Researchers to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

Children's Hospital of The King's Daughters (CHKD) cares for children diagnosed with cancer in southeast Virginia and northeast North Carolina. Clinical trials at CHKD allow for children throughout their great region to access novel agents without traveling far from home. This grant supports the Clinical Research Team to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

Arnold Palmer Hospital for Children is the only site in Florida participating in the Pediatric Oncology Experimental Therapeutics Investigators' Consortium (POETIC) and serves as a referral site for the Beat Childhood Cancer Research Consortium. Dr. Libes-Bander and team's goal is to work toward being able to provide personalized medicine for each child to improve cancer outcomes for children. This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

St. Christopher's Hospital for Children in Philadelphia serves one of the most underserved urban neighborhoods in the nation. This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant supportspersonnel to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

The Renown hematology oncology program was established in 2016 and is the sole provider of pediatric patients with cancer in their region. This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

Kapi'olani Medical Center's unique geographic location allows Dr. Si Lim and colleagues to serve children both within the state of Hawaii, but also other ethnically underrepresented populations such as those from Guam and Micronesia. This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

At SSM Health Cardinal Glennon Children's Hospital, children of all ages receive the highest level of compassionate care, regardless of their family's ability to pay. The skilled professionals at The Costas Center provide multidisciplinary care for a wide variety of cancers, including leukemia and lymphoma, bone and soft tissue cancers, brain and spinal cord tumors and more. Dr. Ferguson and colleagues offer both inpatient and outpatient services in a healing environment designed with children and families in mind. This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

A child diagnosed with rhabdomyosarcoma (RMS) today is subjected to essentially the same therapy used fifty years ago. While Drs Mosse and Maris’s research programs have traditionally focused on neuroblastoma (NBL), both labs have recently extended their research programs to other pediatric solid tumors with high unmet need. Here they propose two parallel and complementary projects designed to create new immunotherapies for RMS, with Project 1 focused on the discovery of new immunoncology targets and cellular therapies, and Project 2 focused on the IND-enabling studies of a novel antibody-drug conjugate (ADC) directed against ALK for fusion positive RMS. This grant is supported by Alice's Arc US Inc. Alice's Arc operates in the UK and USA and is dedicated to funding research into finding a cure and less harsh treatments for rhabdomyosarcoma. The charity has created a global community of families, scientists and doctors coming together to help achieve this mission. Families are at the heart of the work and they can choose to create an Arc in their child/young person's name to represent their experience with rhabdomyosarcoma. This enables funds to be pooled for research, powerful advocacy and a long-term, sustainable platform to grow the charity and fund a pipeline of rhabdomyosarcoma research.

This grant supports funding towards positions to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

Loma Linda University Children's Hospital Foundation works to treat children in the Inland Empire that may be diagnosed with cancer, working to give them the best treatment they can provide. This grant supports a Clinical Research Associate to ensure that more kids can be treated on clinical trials, often their best hope for a cure.

Through this partnership with The Children's Cancer Foundation, proceeds from St. Baldrick's events in Hong Kong fund life-saving research in Hong Kong. The St. Baldrick's Foundation is proud to partner with the Children's Cancer Foundation and has been doing so since 2008.