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Showing 321-340 of 2481 results

Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Calgary, AB
Institution: University of Calgary affiliated with Alberta Children's Hospital

This institution is a member of a research consortium which is being funded by St. Baldrick's: Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC). For a description of this project, see the consortium grant made to the lead institution: National Marrow Donor Program, Minneapolis, MN.

Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Oklahoma City, OK
Institution: University of Oklahoma Health Sciences Center affiliated with The Children's Hospital at OU Medical Center

This institution is a member of a research consortium which is being funded by St. Baldrick's: Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC). For a description of this project, see the consortium grant made to the lead institution: National Marrow Donor Program, Minneapolis, MN.

Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Gainesville, FL
Institution: University of Florida affiliated with Shands Hospital for Children

This institution is a member of a research consortium which is being funded by St. Baldrick's: Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC). For a description of this project, see the consortium grant made to the lead institution: National Marrow Donor Program, Minneapolis, MN.

Anand Bhagwat M.D., Ph.D.

Researcher Photo

Funded: 07-01-2023 through 06-30-2025
Funding Type: St. Baldrick's Fellow
Institution Location: Philadelphia, PA
Institution: The Children's Hospital of Philadelphia affiliated with University of Pennsylvania

Acute Myeloid Leukemia (AML) is a blood cancer that sadly takes the lives of many children each year, and major efforts are being made to save these lives. One idea has been to teach the patient's body to fight off the AML like it would fight off an infection. This strategy alters the patient's immune system by making CAR-T cells, which are cells that fight cancer. CAR-T cells have been successful in curing patients with another similar type of blood cancer, but when it was tried in patients with AML, the approach was less successful. Dr. Anand's project is to understand why it didn't work as well so that further improvements that lead to cures for kids with AML can be made.

This grant is generously supported by the JJ's Angels Hero Fund which honors the memory of Juliana LaMonica and her courageous battle with AML.
Diagnosed at the age of two, Juliana underwent a bone marrow transplant but passed away shortly after turning three. Her sweet spirit and charismatic personality continue to inspire people to support the funding of pediatric cancer research through Team JJ’s Angels.

Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Los Angeles, CA
Institution: Children's Hospital Los Angeles

This institution is a member of a research consortium which is being funded by St. Baldrick's: Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC). For a description of this project, see the consortium grant made to the lead institution: National Marrow Donor Program, Minneapolis, MN.

Reducing Ethnic Disparities in Acute Leukemia (REDIAL) Consortium

Funded: 07-01-2023 through 12-31-2024
Funding Type: Consortium Research Grant
Institution Location: Houston, TX
Institution: Baylor College of Medicine affiliated with Vannie E. Cook Jr. Children's Cancer and Hematology Clinic, Texas Children's Hospital

While great strides have been made in treating children with acute leukemia, some children continue to do poorly. For example, children of Hispanic ethnicity are at greater risk of both relapse and treatment-related complications. The Reducing Ethnic Disparities in Acute Leukemia (REDIAL) Consortium will expand and enhance the recently established network of childhood cancer centers, with the goal of tackling ethnic outcome disparities by generating an unmatched resource of clinical information and biological samples. This information will be used to predict those who have the greatest risk of poor outcomes, with a focus on Hispanics, to improve prevention and treatment strategies. Funds administered by Baylor College of Medicine.

Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Pittsburgh, PA
Institution: Children's Hospital of Pittsburgh affiliated with University of Pittsburgh

This institution is a member of a research consortium which is being funded by St. Baldrick's: Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC). For a description of this project, see the consortium grant made to the lead institution: National Marrow Donor Program, Minneapolis, MN.

Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Miami, FL
Institution: Miller School of Medicine of The University of Miami affiliated with Holtz Children's Hospital

This institution is a member of a research consortium which is being funded by St. Baldrick's: Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC). For a description of this project, see the consortium grant made to the lead institution: National Marrow Donor Program, Minneapolis, MN.

New Approaches to Neuroblastoma Therapy (NANT) Consortium Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Ann Arbor, MI
Institution: C.S. Mott Children’s Hospital affiliated with University of Michigan

This institution is a member of a research consortium which is being funded by St. Baldrick's: New Approaches to Neuroblastoma Therapy (NANT) Consortium. For a description of this project, see the consortium grant made to the lead institution: Children's Hospital Los Angeles, Los Angeles, CA.

Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Palo Alto, CA
Institution: Lucile Packard Children’s Hospital affiliated with Stanford University

This institution is a member of a research consortium which is being funded by St. Baldrick's: Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC). For a description of this project, see the consortium grant made to the lead institution: National Marrow Donor Program, Minneapolis, MN.

Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Charleston, SC
Institution: Medical University of South Carolina affiliated with MUSC Children's Hospital

This institution is a member of a research consortium which is being funded by St. Baldrick's: Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC). For a description of this project, see the consortium grant made to the lead institution: National Marrow Donor Program, Minneapolis, MN.

Srividya Swaminathan Ph.D.

Researcher Photo

Funded: 07-01-2023 through 06-30-2026
Funding Type: St. Baldrick's Scholar
Institution Location: Duarte, CA
Institution: Beckman Research Institute of the City of Hope

Acute Lymphoblastic Leukemia (ALL) are aggressive cancers of B- and T- immune cells. ALL is most common in children but also affects adolescents and young adults. 90% of childhood ALL is curable. However, ~10% of children and ~30% of adolescents and young adults with ALL are not cured. To combat hard-to-treat ALL, Dr. Swaminathan will harness the body’s natural anti-cancer defense mechanism: a type of immune cell called a natural killer (NK) cell. He will also find defective NK cells in children with ALL. Those with fewer defective NK cells tend to survive longer and spend more of their lives free from disease compared to patients with high levels of abnormal NK cells. These findings will inform the development of NK cells as affordable therapies to cure pediatric ALL.

Malignant Germ Cell Tumors International Consortium (MaGIC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Boston, MA
Institution: Dana-Farber Cancer Institute affiliated with Boston Children's Hospital, Harvard Medical School

This institution is a member of a research consortium which is being funded by St. Baldrick's: Malignant Germ Cell Tumors International Consortium (MaGIC). For a description of this project, see the consortium grant made to the lead institution: Dana–Farber Cancer Institute, Boston, MA.

Precision-based Therapy for Childhood Leukemia Consortium Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Atlanta, GA
Institution: Children's Healthcare of Atlanta affiliated with Emory University, Children's Healthcare of Atlanta at Egleston, Aflac Cancer Center

This institution is a member of a research consortium which is being funded by St. Baldrick's: Precision–based Therapy for Childhood Leukemia. For a description of this project, see the consortium grant made to the lead institution: Dana–Farber Cancer Institute, Boston, MA.

Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: San Diego, CA
Institution: Rady Children's Hospital San Diego affiliated with University of California, San Diego

This institution is a member of a research consortium which is being funded by St. Baldrick's: Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC). For a description of this project, see the consortium grant made to the lead institution: National Marrow Donor Program, Minneapolis, MN.

Malignant Germ Cell Tumors International Consortium (MaGIC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Los Angeles, CA
Institution: Children's Hospital Los Angeles

This institution is a member of a research consortium which is being funded by St. Baldrick's: Malignant Germ Cell Tumors International Consortium (MaGIC). For a description of this project, see the consortium grant made to the lead institution: Dana–Farber Cancer Institute, Boston, MA.

Late Effects After High-Risk Neuroblastoma (LEAHRN) Consortium Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Philadelphia, PA
Institution: The Children's Hospital of Philadelphia affiliated with University of Pennsylvania

This institution is a member of a research consortium which is being funded by St. Baldrick's: LEAHRN (Late Effects After High Risk Neuroblastoma) Consortium. For a description of this project, see the consortium grant made to the lead institution: University of Chicago, Chicago, IL.

New Approaches to Neuroblastoma Therapy (NANT) Consortium Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Chicago, IL
Institution: Comer Children's Hospital affiliated with The University of Chicago

This institution is a member of a research consortium which is being funded by St. Baldrick's: New Approaches to Neuroblastoma Therapy (NANT) Consortium. For a description of this project, see the consortium grant made to the lead institution: Children's Hospital Los Angeles, Los Angeles, CA.

Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Boston, MA
Institution: Dana-Farber Cancer Institute affiliated with Boston Children's Hospital, Harvard Medical School

This institution is a member of a research consortium which is being funded by St. Baldrick's: Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC). For a description of this project, see the consortium grant made to the lead institution: National Marrow Donor Program, Minneapolis, MN.

Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC) Member

Funded: 07-01-2023 through 06-30-2024
Funding Type: Consortium Research Grant
Institution Location: Ft. Worth, TX
Institution: Cook Children's Medical Center

This institution is a member of a research consortium which is being funded by St. Baldrick's: Cellular and Immunological Approaches to Prevent Relapse: Pediatric Blood and Marrow Transplant Consortium (PBMTC). For a description of this project, see the consortium grant made to the lead institution: National Marrow Donor Program, Minneapolis, MN.