OUR MISSION
The St. Baldrick's Foundation is a volunteer and donor powered charity committed to supporting the most promising research to find cures for childhood cancers and give survivors long and healthy lives.
Dear Friends,
We live in an age of accelerated scientific and technological advancement. Our rapidly expanding knowledge of the human genome, molecular biology and scores of other disciplines together with the emergence of revolutionary treatments supported by the St. Baldrick's Foundation, such as therapies that use the immune system or target specific genes to kill cancer cells, are improving the futures of children with cancer in ways unforeseen when St. Baldrick's began.
As we embark upon our 20th annual year shaving heads to support childhood cancer research, we celebrate the impact your support and leadership have made in just the last year:
The Childhood Cancer STAR Act, spearheaded by St. Baldrick's, was signed into law thanks to the help of St. Baldrick's advocates, the wider childhood cancer community and our partners in Congress. The law makes it possible to collect samples of blood, tissue, DNA, RNA and other biospecimens and data to accelerate pediatric research. It also supports studies of the incidence, distribution and control of childhood cancers to enable improved care for survivors – a critical need since a recent study funded in part by the St. Baldrick's Foundation found that by the age of 45, 99% of childhood cancer survivors will experience chronic health problems, and 96% will have had a life threatening health issue.
We cannot accept this.
Fortunately, in November 2018 the drug larotrectinib (brand name Vitrakvi) was approved - it's the first treatment developed not for a specific type of cancer, but for any cancer patient with a certain genetic fusion.
We now know cancer is less about where in the body it occurs than what biomarkers and genes are involved. Cancers that previously seemed unrelated are revealing common Achilles' heels that allow advances in one cancer to fight another. While this gives new hope to all cancer patients, it's even more vital for children since most governments, pharmaceutical companies and charities focus principally on adult cancer research.
We were honored to welcome our new partner, the Osteosarcoma Collaborative, whose commitment of $1.5 million has made possible an ambitious grant to develop new ways to treat osteosarcoma patients by targeting molecules that evade immunity. This is the first time the St. Baldrick's Foundation has issued a special call for grant applications for a particular type of childhood cancer, and we expect it to serve as a model for future collaborations with partners and major donors.
These are just a few "wins" for children and teens with cancer that you helped make possible in fiscal year 2017-2018. Advances are made daily, and with your continued support, researchers will realize even more progress in the way children with cancer are treated and saved.
Thank you for helping the St. Baldrick's Foundation take childhood back from cancer.
Michael McCreesh
Chairman of the Board
Father of Brent
Kathleen Ruddy
Chief Executive Officer
Board of Directors
Mike McCreesh, Chair
John R. Bender | Susan L. Cohn, M.D. | Tim Kenny, Treasurer | Jeffrey M. Lipton, M.D., Ph.D. | Katherine Lugar | Thomas Selquist | Kathleen Ruddy | Rebecca Chapman Weaver, Secretary (non-board member)
Board Members Emeritus
Joe Bartlett | Charles M. Chamness | Francis Feeney | Tom Leonhardt | John McKenna
Forever in Our Hearts
Robert J. Arceci, M.D., Ph.D.