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Funding Type: Research Grant
Institution Location: Seattle, WA
Institution: Fred Hutchinson Cancer Research Center affiliated with Seattle Children's Hospital, University of Washington
Childhood acute myeloid leukemia (AML) is the second most common leukemia in children, but causes the majority of leukemia related deaths. Current therapies do not adequately treat the disease and more than half of all children diagnosed with AML eventually relapse and die of their disease. Dr. Meshinchi recently performed a comprehensive genetic analysis of pediatric AML and identified mutations in CSF3R gene, the first pediatric-specific mutation in AML. This JJs Angels St. Baldricks Research Grant aims to study the function of this mutation to learn how it might be used as a therapeutic target. This grant is named for the JJs Angels Hero Fund created in memory of Julianna LaMonica to honor her joyful spirit and strength even in the midst of her battle with cancer. Her story continues to inspire so many to support the cause.