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Pratiti Bandopadhayay M.B.B.S., Ph.D.
Funded: 07-01-2014 through 06-30-2018
Funding Type: St. Baldrick's Scholar
Institution Location: Boston, MA
Institution: Dana-Farber Cancer Institute affiliated with Boston Children's Hospital, Harvard Medical School

Based on progress to date, Dr. Bandopadhayay was awarded a new grant in 2017 to fund an additional year of this Scholar award. Medulloblastoma is the most common malignant brain cancer of childhood. As the Hannah's Heroes St. Baldrick's Scholar, Dr. Bandopadhayay and her lab have shown that the drug JQ1 can hinder the cancer causing effects of a gene called MYC in one of the most aggressive types of medulloblastoma. This project aims to identify drugs which can be added to JQ1 to improve effectiveness. The results of this project will help determine combination therapies that can be used to treat children with this aggressive type of brain tumor. This grant is named for Hannah’s Heroes, a St. Baldrick’s Hero Fund created in honor of Hannah Meeson and pays tribute to her fight by raising awareness and funding for all childhood cancers because kids like Hannah “are worth fighting for.”