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Alex Huang M.D., Ph.D.
Funded: 07-01-2017 through 06-30-2018
Funding Type: St. Baldrick's Foundation Innovation Award
Institution Location: Cleveland, OH
Institution: Case Western Reserve University

Our immune system has a remarkable ability to eradicate a vast array of foreign invaders. With increasing knowledge of this remarkable organ system, we can now begin to manipulate our immune system to fight cancer with remarkable precision and efficacy. However; tumor cells adopt multiple ways to reduce the immunotherapy efficacy, especially for solid tumors. Dr. Huang’s research program systematically studies ways by which cancer cells evade immune cell detection and his goal is to develop a comprehensive, multi-pronged approach to increase the overall effectiveness of immunotherapy, particularly in pediatric and adolescent and young adult brain tumors and solid tumors.