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Alex Huang M.D., Ph.D.
Funded: 01-01-2015 through 12-31-2015
Funding Type: Infrastructure Grant
Institution Location: Cleveland, OH
Institution: Case Western Reserve University

This grant helps provide the resources to establish a live-cell pediatric solid tumor banking system.

Alex Huang M.D., Ph.D.
Funded: 12-01-2008 through 11-30-2013
Funding Type: St. Baldrick's Scholar
Institution Location: Cleveland, OH
Institution: Case Western Reserve University

Based on progress to date, Dr. Huang was awarded a new grant in 2011 to fund an additional two years of this Scholar award. Pediatric patients with metastatic sarcomas (cancers of connective tissues, like bone or muscle, with cancer that has spread) have a low rate of cure. Recent evidence suggests that the immune system plays a critical role in tumor spread. Unfortunately, aggressive systemic chemotherapy used to treat pediatric sarcoma patients devastates the ability of immune system to harness the anti-tumor properties. Dr. Huang's research aims to incorporate the immunological arm of cancer therapy into standard therapeutic protocols, to provide life-saving treatments for children with osteosarcoma and rhabdomyosarcoma.